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中文名称：小鼠白介素12(IL-12/P70)酶联免疫试剂盒
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货号：CSB-E04600m
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规格：96T/48T
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价格：￥3200/￥2500
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其他：
产品详情
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产品描述：CUSABIO专用于科研领域的小鼠白介素12（IL-12/P70）酶联免疫检测试剂盒（货号CSB-E04600m），采用双抗体夹心法原理实现定量分析。IL-12/P70是一种由抗原呈递细胞分泌的异源二聚体细胞因子，在Th1型免疫应答诱导、NK细胞活化及抗肿瘤免疫中发挥核心调控作用，其表达水平与感染性疾病、自身免疫病及肿瘤微环境密切相关。该试剂盒检测范围覆盖62.5 pg/mL至4000 pg/mL，适用于血清、血浆及组织匀浆样本的定量检测，能够精准分析不同实验条件下IL-12/P70的动态变化。科研人员可将其应用于免疫调节机制研究、炎症性疾病模型评估、肿瘤免疫治疗药物开发等基础研究领域，为探索IL-12在先天性与适应性免疫中的分子机制提供可靠工具。试剂盒严格遵循科研级质量标准生产，配套标准品与优化缓冲体系确保实验数据的稳定性和重复性，是体外实验研究中细胞因子定量检测的高效解决方案。
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别名：N/A
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缩写：IL-12/P70
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种属：Mus musculus (Mouse)
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样本类型：serum, plasma, tissue homogenates
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检测范围：62.5 pg/ml - 4000 pg/ml
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灵敏度：15.6 pg/ml
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Immunology
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测定原理：quantitative
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测定方法：Sandwich
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精密度：
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回收率：
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标准曲线：
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数据处理：
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货期：3-5 working days
引用文献
- IL-12-Overexpressed Nanoparticles Suppress the Proliferation of Melanoma Through Inducing ICD and Activating DC, CD8+ T, and CD4+ T Cells HH Shen,International journal of nanomedicine,2024
- Gene engineered exosome reverses T cell exhaustion in cancer immunotherapy X Qin,Bioactive materials,2024
- YAP/STAT3 inhibited CD8+ T cells activity in the breast cancer immune microenvironment by inducing M2 polarization of tumor‐associated macrophages C Wang,Cancer medicine,2023
- Enforced mesenchymal stem cell tissue colonization counteracts immunopathology D García-Bernal,NPJ Regenerative Medicine,2022
- Secretions from hypochlorous acid-treated tumor cells delivered in a melittin hydrogel potentiate cancer immunotherapy Y Zhou,Bioactive materials,2022
- Secretions from hypochlorous acid-treated tumor cells delivered in a melittin hydrogel potentiate cancer immunotherapy Y Zhou,Bioactive Materials,2021
- Toxoplasma gondii ROP16I Deletion: The Exacerbated Impact on Adverse Pregnant Outcomes in Mice W Cui,Front Microbiol.,2020
- Gluthathione S-transferase-resuscitation-promoting factor B recombinant protein of Mycobacterium tuberculosis induces the production of interferon-γ and interleukin-12 in mice splenocytes Rukmana A, et al,Medical Journal of Indonesia,2019
- Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation Zheng J, et al,Nature Communications,2019
- Suppressive oligodeoxynucleotide-induced dendritic cells rein the aggravation of osteoarthritis in mice Guo W, et al,Immunopharmacol Immunotoxicol,2018
- A Polysaccharide from Amusium Pleuronectes Combined with Praziquantel Treatment Ameliorates Hepatic Fibrosis in Schistosoma Japonicum-Infected Mice Tang X.et al,Med Sci Monit,2018
- Vaccination with FasL-/TCL plus MHSP65 induces improved anti-lung cancer immunity in mice Dong B.et al,Int Immunopharmacol,2018
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靶点详情
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最新研究进展：IL12/P70是一种由多种细胞产生的细胞因子，对于刺激和调节免疫反应至关重要。最近的研究表明，IL12/P70参与了多种疾病的发展和治疗。例如，一些研究表明，IL12/P70能够促进肿瘤细胞的免疫清除，并在癌症治疗中具有潜在的作用。此外，IL12/P70还被用于治疗炎症性疾病，如炎症性肠病和乙型肝炎。
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