冠状病毒
冠状病毒是一类通常影响鸟类和哺乳动物，包括人类呼吸道的病毒。"冠状病毒"一词来源于其表面的冠状突起。拉丁文中，“corona”意为“光环”或“王冠”。
科学家最早于1937年分离出一种冠状病毒，他们发现一种冠状病毒是鸟类传染性支气管炎病毒，有能力摧毁家禽存栏。冠状病毒亚科的成员在哺乳动物中广泛分布，通常只引起轻微的呼吸道或肠道感染。超过60种冠状病毒（CoVs）已从蝙蝠（BtCoV）中分离出来，其中大多数属于β冠状病毒属。
人类冠状病毒（HCoVs）
人类冠状病毒（HCoVs）属于Nidovirales目，Coronaviridae科，Coronavirinae亚科，Alphacoronavirus属或Betacoronavirus属。上世纪60年代在感冒患者的鼻子中首次发现了HCoVs，它们代表了与多种呼吸道疾病相关的冠状病毒（CoVs）的一个主要群体，包括普通感冒、肺炎和支气管炎等 [1]。它们通常引起短暂的呼吸道或胃肠道疾病。
迄今为止，已经确定了七种已知的HCoVs，即HCoV-229E、HCoV-NL63、HCoV-OC43、HCoV-HKU1、严重急性呼吸综合症冠状病毒（SARS-CoV）、中东呼吸综合症冠状病毒（MERS-CoV）和2019新型冠状病毒（SARS-CoV-2）。
其中，四种HCoVs（HCoV-229E、HCoV-NL63、HCoV-OC43和HCoV-HKU1）在人群中广泛传播，占人类普通感冒感染的约三分之一 [2]。
Human Novel Coronavirus (SARS-CoV-2)
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Human Novel Coronavirus Non-structural protein 8 (ns8) | NSP8 | E.coli | N-terminal 6xHis-tagged | CSB-EP3366GND |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Non-structural protein 9 (nsp9) | Nsp9 | Mammalian cell | C-terminal hFc-Flag-tagged | CSB-MP3388GND |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Non-structural protein 9 (nsp9) | Nsp9 | E.coli | C-terminal 10xHis-tagged | CSB-EP3388GND |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Envelope small membrane protein & Membrane protein (E & M), partial | E & M | E.coli | N-terminal 6xHis-SUMO-tagged | CSB-EP3402GND |
| Recombinant Severe acute respiratory syndrome coronavirus 2 RNA-dependent RNA polymerase (NSP12) | NSP12 | E.coli | N-terminal 6xHis-tagged | CSB-EP3371GND |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (T205I) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M2) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (P80R) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M3) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (P13L) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M4) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (D103Y) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M5) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (L230F) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M9) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (I292T) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M10) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (Q384H) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M11) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (R203K,G204R) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M12) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (D3L,R203K,G204R,S235F) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M1) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (S202N) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M8) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (R203M,D377Y) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M13) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N) (D63G,R203M,D377Y) (Active) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP3325GMY(M14) |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N), partial | N | E.coli | C-terminal 10xHis-tagged | CSB-EP3325GMY1 |
| Recombinant Severe acute respiratory syndrome coronavirus 2 Nucleoprotein (N), Biotinylated | N | E.coli | N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged | CSB-EP3325GMY-B |
Human SARS coronavirus (SARS-CoV)
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Human SARS coronavirus Protein non-structural 7b (7b), partial | 7b | E.coli | N-terminal GST-tagged | CSB-EP756006HQE |
| Recombinant Human SARS coronavirus Nucleoprotein (N) | N | Baculovirus | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-BP349523HQE |
| Recombinant Human SARS coronavirus Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP349523HQE |
| Recombinant Human SARS coronavirus Spike glycoprotein (S), partial (Active) | S | Mammalian cell | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-MP348663HQE |
| Recombinant Human SARS coronavirus Spike glycoprotein (S), partial | S | Yeast | N-terminal 6xHis-tagged | CSB-YP348663HQE |
| Recombinant Human SARS coronavirus Spike glycoprotein (S), partial | S | Yeast | N-terminal 6xHis-sumostar-tagged | CSB-YP348663HQEa4 |
| Recombinant Severe acute respiratory syndrome coronavirus 3C-like proteinase, partial | N/A | in vitro E.coli expression system | N-terminal 10xHis-tagged | CSB-CF3621GOU |
| Recombinant Severe acute respiratory syndrome coronavirus Spike glycoprotein (S), partial | S | Mammalian cell | C-terminal 6xHis-tagged | CSB-MP348663HQEc7 |
| Recombinant SARS coronavirus MA15 3C-like proteinase, partial | N/A | in vitro E.coli expression system | N-terminal 10xHis-tagged | CSB-CF3622GOV |
Human coronavirus 229E (HCoV-229E)
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Human coronavirus 229E Membrane protein (M), partial | M | E.coli | N-terminal 10xHis-tagged | CSB-EP323624HIT1 |
| Recombinant Human coronavirus 229E Nucleoprotein (N) | N | Mammalian cell | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-MP322753HIT |
| Recombinant Human coronavirus 229E Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP322753HIT |
| Recombinant Human coronavirus 229E Nucleoprotein (N) | N | Baculovirus | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-BP322753HIT |
| Recombinant Human coronavirus 229E Nucleoprotein (N) | N | Mammalian cell | C-terminal 6xHis-tagged | CSB-MP322753HITc7 |
| Recombinant Human coronavirus 229E Nucleoprotein (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP322753HITc7 |
| Recombinant Human coronavirus 229E Spike glycoprotein (S), partial | S | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-EP321366HIT |
| Recombinant Human coronavirus 229E Spike glycoprotein (S), partial | S | Mammalian cell | C-terminal 6xHis-tagged | CSB-MP321366HIT1 |
Human coronavirus HKU1 (isolate N1) (HCoV-HKU1)
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Human coronavirus HKU1 Non-structural protein 4 (4) | 4 | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-EP689643HIU |
| Recombinant Human coronavirus HKU1 Non-structural protein 4 (4) | 4 | E.coli | C-terminal 6xHis-tagged | CSB-EP689643HIUc7 |
| Recombinant Human coronavirus HKU1 Non-structural protein 4 (4) | 4 | Baculovirus | C-terminal 6xHis-tagged | CSB-BP689643HIUc7 |
| Recombinant Human coronavirus HKU1 Non-structural protein 4 (4) | 4 | Yeast | C-terminal 6xHis-tagged | CSB-YP689643HIU |
| Recombinant Human coronavirus HKU1 Nucleoprotein (N) | N | Baculovirus | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-BP683657HIU |
| Recombinant Human coronavirus HKU1 Nucleoprotein (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP683657HIUc7 |
| Recombinant Human coronavirus HKU1 Protein I (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP683656HIUc7 |
| Recombinant Human coronavirus HKU1 Protein I (N) | N | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-EP683656HIU |
| Recombinant Human coronavirus HKU1 Spike glycoprotein (S), partial | S | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-EP708794HIU |
| Recombinant Human coronavirus HKU1 Spike glycoprotein (S), partial | S | E.coli | C-terminal 6xHis-tagged | CSB-EP708794HIUc7 |
| Recombinant Human coronavirus HKU1 Hemagglutinin-esterase (HE) | HE | in vitro E.coli expression system | N-terminal 10xHis-tagged | CSB-CF613540HIV |
| Recombinant Human coronavirus HKU1 Spike glycoprotein (S), partial | S | E.coli | C-terminal 6xHis-tagged | CSB-EP618924HIV |
| Recombinant Human coronavirus HKU1 Spike glycoprotein (S), partial | S | Yeast | C-terminal 6xHis-tagged | CSB-YP618924HIV |
| Recombinant Human coronavirus HKU1 Non-structural protein 4 (4) | 4 | E.coli | N-terminal 6xHis-tagged | CSB-EP608711HIW |
| Recombinant Human coronavirus HKU1 Non-structural protein 4 (4) | 4 | Yeast | C-terminal 6xHis-tagged | CSB-YP608711HIW |
| Recombinant Human coronavirus HKU1 Nucleoprotein (N) | N | Mammalian cell | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-MP607323HIW |
| Recombinant Human coronavirus HKU1 Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP607323HIW |
| Recombinant Human coronavirus HKU1 Protein I (N) | N | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-EP605916HIW |
| Recombinant Human coronavirus HKU1 Nucleoprotein (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP607323HIWc7 |
| Recombinant Human coronavirus HKU1 Spike glycoprotein (S), partial | S | Mammalian cell | C-terminal mFc-tagged | CSB-MP611894HIWh8 |
| Recombinant Human coronavirus HKU1 Spike glycoprotein (S), partial | S | E.coli | C-terminal 6xHis-tagged | CSB-EP611894HIW |
| Recombinant Human coronavirus HKU1 Spike glycoprotein (S), partial | S | Yeast | C-terminal 6xHis-tagged | CSB-YP611894HIW |
Human coronavirus NL63 (HCoV-NL63)
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Human coronavirus NL63 Envelope small membrane protein (E) | E | in vitro E.coli expression system | N-terminal 10xHis-tagged | CSB-CF764822HIX |
| Recombinant Human coronavirus NL63 Membrane protein (M) | M | in vitro E.coli expression system | N-terminal 10xHis-tagged | CSB-CF757672HIX |
| Recombinant Human coronavirus NL63 Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP744150HIX |
| Recombinant Human coronavirus NL63 Nucleoprotein (N) | N | Baculovirus | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-BP744150HIX |
| Recombinant Human coronavirus NL63 Spike glycoprotein (S), partial | S | Yeast | N-terminal 6xHis-sumostar-tagged | CSB-YP747509HIX1 |
| Recombinant Human coronavirus NL63 Spike glycoprotein (S), partial | S | Yeast | N-terminal 6xHis-PDI-tagged | CSB-YP747509HIX |
Human coronavirus OC43 (HCoV-OC43)
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Human coronavirus OC43 Non-structural protein 2a (2a) | 2a | Baculovirus | C-terminal 6xHis-tagged | CSB-BP767285HIY |
| Recombinant Human coronavirus OC43 Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP333798HIY |
| Recombinant Human coronavirus OC43 Nucleoprotein (N) | N | Mammalian cell | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-MP333798HIY |
| Recombinant Human coronavirus OC43 Nucleoprotein (N) | N | Mammalian cell | C-terminal hFc-tagged | CSB-MP333798HIYd9 |
| Recombinant Human coronavirus OC43 Nucleoprotein (N) | N | Baculovirus | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-BP333798HIY |
| Recombinant Human coronavirus OC43 Protein I (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP700347HIY |
| Recombinant Human coronavirus OC43 Spike glycoprotein (S), partial | S | E.coli | N-terminal 6xHis-SUMO-tagged | CSB-EP336163HIY |
| Recombinant Human coronavirus OC43 Spike glycoprotein (S), partial | S | Baculovirus | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-BP336163HIY |
| Recombinant Human coronavirus OC43 Spike glycoprotein (S), partial | S | Yeast | N-terminal 6xHis-tagged | CSB-YP336163HIY |
| Recombinant Human coronavirus OC43 Spike glycoprotein (S), partial | S | Mammalian cell | C-terminal 6xHis-Myc-tagged | CSB-MP336163HIY1 |
| Recombinant Human coronavirus OC43 Spike glycoprotein (S), partial | S | E.coli | C-terminal 6xHis-tagged | CSB-EP336163HIY1 |
Human betacoronavirus
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Human betacoronavirus 2c EMC/2012 Spike glycoprotein (S), partial | S | Yeast | N-terminal 6xHis-sumostar-tagged | CSB-YP3416GNJa4 |
| Recombinant Human betacoronavirus 2c EMC/2012 Spike glycoprotein (S), partial | S | Yeast | N-terminal 6xHis-tagged | CSB-YP3416GNJ |
| Recombinant Human betacoronavirus 2c EMC/2012 Spike glycoprotein (S), partial | S | Mammalian cell | C-terminal 6xHis-tagged | CSB-MP3416GNJ |
| Recombinant Human betacoronavirus 2c EMC/2012 Spike glycoprotein (S), partial | S | Mammalian cell | C-terminal mFc-tagged | CSB-MP3416GNJh8 |
Bat coronavirus
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Bat coronavirus 133/2005 Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP605318BFA |
| Recombinant Bat coronavirus 133/2005 Nucleoprotein (N) | N | Baculovirus | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-BP605318BFA |
| Recombinant Bat coronavirus 133/2005 Spike glycoprotein (S), partial | S | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-EP610383BFA |
| Recombinant Bat coronavirus HKU3 Nucleoprotein2 (N) | N | Baculovirus | C-terminal 6xHis-tagged | CSB-BP664686BFDc7 |
| Recombinant Bat coronavirus HKU3 Nucleoprotein2 (N) | N | Baculovirus | C-terminal 6xHis-tagged | CSB-BP664686BFD |
| Recombinant Bat coronavirus HKU3 Spike glycoprotein (S), partial | S | Baculovirus | C-terminal 6xHis-tagged | CSB-BP663395BFD |
| Recombinant Bat coronavirus HKU3 Spike glycoprotein (S), partial | S | E.coli | N-terminal 6xHis-tagged | CSB-EP663395BFD |
| Recombinant Bat coronavirus HKU4 Nucleoprotein (N) | N | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-EP387608BOT |
| Recombinant Bat coronavirus HKU5 Nucleoprotein (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP386462BOU |
| Recombinant Bat coronavirus HKU9 Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP385259BOVa0 |
| Recombinant Bat coronavirus HKU9 Nucleoprotein (N) | N | Baculovirus | C-terminal 6xHis-tagged | CSB-BP385259BOV |
| Recombinant Bat coronavirus HKU9 Spike glycoprotein (S), partial | S | E.coli | N-terminal 6xHis-tagged | CSB-EP385258BOV |
| Recombinant Bat coronavirus HKU9 Spike glycoprotein (S), partial | S | Baculovirus | C-terminal 6xHis-tagged | CSB-BP385258BOV |
Bovine coronavirus
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Bovine coronavirus Non-structural protein 2a (2a) | 2a | Yeast | C-terminal 6xHis-tagged | CSB-YP838639BJE |
| Recombinant Bovine coronavirus Non-structural protein 2a (2a) | 2a | Baculovirus | C-terminal 6xHis-tagged | CSB-BP838639BJE |
| Recombinant Bovine coronavirus Protein I (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP852737BJE |
| Recombinant Bovine coronavirus Spike glycoprotein (S), partial | S | Yeast | C-terminal 6xHis-tagged | CSB-YP820951BJE |
| Recombinant Bovine coronavirus Non-structural protein 2a (2a) | 2a | Mammalian cell | C-terminal 6xHis-tagged | CSB-MP855307BJF |
| Recombinant Bovine coronavirus Non-structural protein of 4.8 kDa (4b) | 4b | Yeast | C-terminal 6xHis-tagged | CSB-YP314697BJF |
| Recombinant Bovine coronavirus Non-structural protein of 12.7 kDa (5a) | 5a | E.coli | C-terminal 6xHis-tagged | CSB-EP848658BJF |
| Recombinant Bovine coronavirus Non-structural protein of 12.7 kDa (5a) | 5a | Baculovirus | C-terminal 6xHis-tagged | CSB-BP848658BJF |
| Recombinant Bovine coronavirus Nucleoprotein (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP823718BJF |
| Recombinant Bovine coronavirus Protein I (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP844974BJF |
| Recombinant Bovine coronavirus Spike glycoprotein (S), partial | S | Mammalian cell | C-terminal 6xHis-tagged | CSB-MP819726BJF |
| Recombinant Bovine coronavirus Nucleoprotein (N) | N | Mammalian cell | C-terminal 6xHis-tagged | CSB-MP321743BJG |
| Recombinant Bovine coronavirus Spike glycoprotein (S), partial | S | Yeast | C-terminal 6xHis-tagged | CSB-YP326525BJG |
| Recombinant Bovine coronavirus Spike glycoprotein (S), partial | S | Yeast | C-terminal 6xHis-tagged | CSB-YP338650BJH |
| Recombinant Bovine coronavirus Non-structural protein 2a (2a) | 2a | Baculovirus | C-terminal 6xHis-tagged | CSB-BP313890BJI |
| Recombinant Bovine coronavirus Non-structural protein 2a (2a) | 2a | E.coli | C-terminal 6xHis-tagged | CSB-EP313890BJI |
| Recombinant Bovine coronavirus Nucleoprotein (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP889516BJI |
| Recombinant Bovine coronavirus Protein I (N) | N | E.coli | C-terminal 6xHis-tagged | CSB-EP868731BJI |
| Recombinant Bovine coronavirus Spike glycoprotein (S), partial | S | Mammalian cell | C-terminal 6xHis-tagged | CSB-MP874069BJI |
| Recombinant Bovine coronavirus Spike glycoprotein (S), partial | S | E.coli | C-terminal 6xHis-tagged | CSB-EP874069BJI |
Canine coronavirus
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Canine coronavirus Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP745849CHAH |
| Recombinant Canine coronavirus Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP327521CCO |
| Recombinant Canine coronavirus Nucleoprotein (N) | N | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-EP327521CCOb1 |
| Recombinant Canine coronavirus Nucleoprotein (N) | N | E.coli | N-terminal 6xHis-tagged | CSB-EP312949CCP |
Feline coronavirus
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Feline coronavirus Non-structural protein 7a (7a), partial | 7a | E.coli | N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged | CSB-EP321722FEJ |
| Recombinant Feline coronavirus Spike glycoprotein (S), partial | S | E.coli | C-terminal 6xHis-tagged | CSB-EP319859FEJ |
| Recombinant Feline coronavirus Spike glycoprotein (S), Partial | S | E.coli | N-terminal GST-tagged | CSB-EP319859FEJ1e0 |
| Recombinant Feline coronavirus Spike glycoprotein (S), Partial | S | E.coli | C-terminal 6xHis-tagged | CSB-EP319859FEJ1 |
| Recombinant Feline coronavirus Spike glycoprotein (S), Partial | S | E.coli | N-terminal 6xHis-SUMO-tagged | CSB-EP319859FEJ1a2 |
Other coronavirus
| Product Name | Target | Source | Tag Info | Product Code |
|---|---|---|---|---|
| Recombinant Middle East respiratory syndrome-related coronavirus Orf1ab, partial | N/A | E.coli | Tag-Free | CSB-EP2883GJE |
| Recombinant Porcine transmissible gastroenteritis coronavirus Nucleoprotein (N) | N | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged | CSB-EP361212PQH |
冠状病毒的传播
冠状病毒可以从一个人传播到另一个人，科学家认为这些病毒通过呼吸系统中的液体，如黏液，传播。冠状病毒可以通过以下方式传播：
● 通过咳嗽和打喷嚏而进入空气中
● 密切的个人接触，比如触摸或握手
● 接触带有病毒的物体或表面，然后在洗手之前触摸口、鼻或眼睛
由冠状病毒引起的疾病
人类冠状病毒通常导致普通感冒而非严重疾病。然而，冠状病毒也是一些更严重爆发的原因，如严重急性呼吸综合症（SARS）、中东呼吸综合症（MERS）和COVID-19。
SARS
SARS是由一种冠状病毒引起的病毒性呼吸道疾病，称为严重急性呼吸综合症相关冠状病毒（SARS-CoV）。通常，它导致一种危及生命的肺炎。SARS首次于2002年11月在亚洲报告。在接下来的几个月里，这种疾病在北美、南美、欧洲和亚洲的两打国家传播，直到2003年SARS全球爆发得到控制 [3]。
根据世界卫生组织（WHO）的数据，在SARS爆发期间，全球共有8,098人感染SARS，其中774人死亡。这相当于9.6%的死亡率。
SARS的症状在一周的过程中逐渐发展，开始于发热。在疾病的早期阶段，人们会出现类似流感的症状，如干咳、寒战、腹泻、呼吸急促和疼痛。通常会发展为严重的肺部感染。在其最高级阶段，SARS会导致肺部、心脏或肝脏的功能衰竭。
MERS
MERS是由一种冠状病毒引起的，被称为中东呼吸综合症冠状病毒（MERS-CoV）。科学家在2012年首次识别了这种严重的呼吸系统疾病，当时它在沙特阿拉伯爆发。从那时起，它传播到其他国家。MERS-CoV引起的临床症状与SARS-CoV相似，但死亡率要高得多，约为35% [4]。
MERS的症状包括发热、呼吸急促和咳嗽。该疾病通过与已经感染的人密切接触传播。然而，所有MERS的病例都与最近从阿拉伯半岛旅行归来的个体有关。
COVID-19
2019年，疾病预防控制中心（CDC）开始监测一种新型冠状病毒，SARS-CoV-2，导致现在被称为COVID-19的呼吸系统疾病的爆发。COVID-19的症状因人而异。它可能只引起很少或没有症状。然而，它也可能导致严重的疾病，甚至致命。常见症状包括发热、呼吸急促和咳嗽。有关COVID-19的更多信息，请阅读2019新型冠状病毒。
相关试剂产品
参考文献：
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