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中文名称：人血血小板衍生生长因子AB(PDGF-AB)酶联免疫试剂盒
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货号：CSB-E04701h
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规格：96T/48T
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价格：￥3200/￥2500
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其他：
产品详情
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产品描述：人血血小板衍生生长因子AB(PDGF-AB)酶联免疫试剂盒（CSB-E04701h）为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的PDGF-AB含量。PDGF-AB是一种由血小板分泌的生长因子，由A和B链组成，参与调控纤维母细胞和平滑肌细胞等中胚层来源细胞的增殖和迁移。其研究机制涉及PDGF与PDGFRα和PDGFRβ受体的结合，激活下游信号通路，促进细胞增殖和血管生成。试剂盒检测范围为31.25 pg/mL-2000 pg/mL，灵敏度为7.8 pg/mL。适用于体外实验中对PDGF-AB的定量分析，例如探究心血管疾病模型中的信号通路机制、评估药物干预对细胞因子表达的影响，或通过组织样本分析疾病相关分子标志物变化，为细胞生物学、病理学及药理学研究提供可靠数据支持。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
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缩写：PDGF-AB
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种属：Homo sapiens (Human)
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样本类型：serum, plasma, tissue homogenates
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检测范围：31.25 pg/mL-2000 pg/mL
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灵敏度：7.8 pg/mL
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Cancer
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测定原理：quantitative
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测定方法：Sandwich
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.Inter-assay Precision (Precision between assays): CV%<10%Three samples of known concentration were tested in twenty assays to assess. -
线性度：
To assess the linearity of the assay, samples were spiked with high concentrations of human PDGF-AB in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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回收率：
The recovery of human PDGF-AB spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
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标准曲线：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
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数据处理：
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货期：3-5 working days
引用文献
- Differences in injectable platelet-rich fibrin fraction of peripheral blood on the release of TGF-β1 and PDGF-AB S Suryono,Majalah Kedokteran Gigi Indonesia,2023
- A comparative study of the effects of concentrated growth factors in two different forms on osteogenesis in vitro Wang L,Molecular Medicine Reports,2019
- Chitosan scaffold enhances growth factor release in wound healing in von Willebrand disease Periayah MH. et al,Int J Clin Exp Med,2015
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靶点详情
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最新研究进展：PDGF-AB是血小板源性生长因子（platelet-derived growth factor，PDGF）家族的一个亚型，由PDGF-A和PDGF-B两个亚基组成。最近的研究表明，PDGF-AB参与了多种生物学过程，如细胞增殖、分化、迁移和细胞外基质合成等。此外，PDGF-AB在多种疾病中也发挥着重要作用，如肿瘤、动脉粥样硬化和组织损伤等。因此，PDGF-AB成为了治疗靶点的研究热点。一些研究已经探索了PDGF-AB的抑制剂和抗体，以期望发现更有效的治疗方案。
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