ROCK1
ROCK1，即Rho相关卷曲螺旋激酶1，别名Rho激酶1、ROK-β、p160-ROCK。它是一种由ROCK1基因编码的丝氨酸/苏氨酸蛋白激酶，属于Rho/ROCK信号通路的关键组成部分。ROCK1的作用机制主要是通过磷酸化多种底物蛋白，如肌球蛋白轻链、LIM激酶等，参与调节细胞形态、运动、收缩和增殖等生理过程。ROCK1在调控细胞骨架重组、细胞迁移、血管内皮通透性以及组织收缩和生长等多种生理功能中发挥重要作用。此外，ROCK1的功能异常与糖尿病肾病、眼疾病、肿瘤、心脏病、神经损伤性疾病、高血压等多种疾病的发生发展有关，是药物研发中的潜在靶点。
热销产品
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA057038(ROCK1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA057038(ROCK1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
ROCK1 Antibodies
ROCK1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA020058GA01HU | ROCK1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004017 | ROCK1 Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA040230 | ROCK1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA057038 | ROCK1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA679461 | ROCK1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA614415HA01HU | ROCK1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA614415HB01HU | ROCK1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA614415HC01HU | ROCK1 Antibody, FITC conjugated | Human | |
| CSB-PA614415HD01HU | ROCK1 Antibody, Biotin conjugated | Human | ELISA |
ROCK1 Proteins
ROCK1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP020058MO CSB-EP020058MO CSB-BP020058MO CSB-MP020058MO CSB-EP020058MO-B |
Recombinant Mouse Rho-associated protein kinase 1 (Rock1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP020058RB CSB-EP020058RB CSB-BP020058RB CSB-MP020058RB CSB-EP020058RB-B |
Recombinant Rabbit Rho-associated protein kinase 1 (ROCK1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Pan troglodytes (Chimpanzee)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP020058EQV CSB-EP020058EQV CSB-BP020058EQV CSB-MP020058EQV CSB-EP020058EQV-B |
Recombinant Pan troglodytes Rho-associated protein kinase 1 (ROCK1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP614415HU CSB-EP614415HU CSB-BP614415HU CSB-MP614415HU CSB-EP614415HU-B |
Recombinant Human Rho-associated protein kinase 1 (ROCK1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP717402RA CSB-EP717402RA CSB-BP717402RA CSB-MP717402RA CSB-EP717402RA-B |
Recombinant Rat Rho-associated protein kinase 1 (Rock1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK1 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP847572BO CSB-EP847572BO CSB-BP847572BO CSB-MP847572BO CSB-EP847572BO-B |
Recombinant Bovine Rho-associated protein kinase 1 (ROCK1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
