Mouse procollagen Ⅰ N-terminal peptide,PⅠNP ELISA Kit

Mouse procollagen Ⅰ N-terminal peptide,PⅠNP ELISA Kit

产品详情

引用文献

产品详情

引用文献

产品评价

相关产品

Most popular with customers

产品中心

信号通路

技术信息

联系信息

中文名称：

小鼠Ⅰ型前胶原N端前肽(PⅠNP)酶联免疫试剂盒
货号：

CSB-E12775m
规格：

96T/48T
价格：

￥3600/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star™ Award in the ELISA category

产品详情
产品评价
引用文献
相关产品

产品描述：

小鼠Ⅰ型前胶原N端前肽(PⅠNP)酶联免疫试剂盒（CSB-E12775m）为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的PⅠNP含量。PⅠNP是一种重要靶点。其与骨代谢密切相关，可反映成骨细胞活性。研究机制上，通过检测血液中其含量变化，能评估骨形成状态，在骨质疏松等骨骼疾病的诊断、病情监测及治疗效果评估等研究中发挥着关键作用。试剂盒检测范围为4.7 pg/mL-300 pg/mL，PⅠNP可作为骨形成和纤维化进程的关键生物标志物，在骨代谢研究、纤维化疾病模型评估及药物干预效果分析中具有重要科研价值。适用于研究骨发育异常、骨质疏松模型、肝/肺纤维化机制探索等科研领域，为相关疾病模型的生物标志物分析提供可靠工具。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：

procollagen 1 N-terminal peptide,P1NP,_x000D_ procollagen I N-terminal peptide,PINP
缩写：

PⅠNP
种属：

Mus musculus (Mouse)
样本类型：

serum, plasma, tissue homogenates
检测范围：

4.7 pg/mL-300 pg/mL
灵敏度：

1.17 pg/mL
反应时间：

1-5h
样本体积：

50-100ul
检测波长：

450 nm
研究领域：

Others
测定原理：

quantitative
测定方法：

Sandwich

精密度：

线性度：

To assess the linearity of the assay, samples were spiked with high concentrations of mouse PINP in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
	Sample	Serum(n=4)
1:100	Average %	92
	Range %	87-98
1:200	Average %	95
	Range %	91-98
1:400	Average %	91
	Range %	85-96
1:800	Average %	94
	Range %	88-102

回收率：

The recovery of mouse PINP spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

Sample Type	Average % Recovery	Range
Serum (n=5)	96	89-99
EDTA plasma (n=4)	89	82-94

标准曲线：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

pg/ml	OD1	OD2	Average	Corrected
300	2.413	2.313	2.363	2.261
150	1.598	1.498	1.548	1.446
75	0.940	0.890	0.915	0.813
37.5	0.489	0.479	0.484	0.382
18.75	0.316	0.306	0.311	0.209
9.4	0.207	0.205	0.206	0.104
4.7	0.145	0.142	0.144	0.042
0	0.103	0.101	0.102

数据处理：

ELISA操作视频及标曲绘制软件下载
货期：

3-5 working days

Stephanine Protects Against Osteoporosis by Suppressing Osteoclastogenesis via Inhibition of the RANKL—RANK Interaction T Liu, J Li, M Duan, Y Wang, Z Jiang,Journal of Cellular and Molecular Medicine,2024
Altered post-fracture systemic bone loss in a mouse model of osteocyte dysfunction B Osipov, AJ Emami, HC Cunningham, S Orr,JBMR plus,2024
FOXO1-mTOR pathway in vascular pericyte regulates the formation of type H vessels to control bone metabolism C Cheng, M Deng, C Cheng, H Wu, Y Wang,Journal of Orthopaedic Translation,2024
Hybrid complex of tyrosinase and carbon-based materials for tissue engineering applications 고중현,서울대학교 대학원,2024
Single-Walled Carbon Nanotube-Guided Topical Skin Delivery of Tyrosinase to Prevent Photoinduced Damage J Ko,ACS nano,2023
FNDC5/irisin ameliorates bone loss of type 1 diabetes by suppressing endoplasmic reticulum stress_x001e_mediated ferroptosis Q Dong,Journal of orthopaedic surgery and research,2024
Activation of TAZ by XMU-MP-1 inhibits osteoclastogenesis and attenuates ovariectomy-induced cancellous bone loss X Li,Biochemical and biophysical research communications,2023
Icariin, a phytoestrogen, exerts rapid estrogenic actions through crosstalk of estrogen receptors in osteoblasts KY Wong,Phytotherapy research,2023
Bone-targeting engineered small extracellular vesicles carrying anti-miR-6359-CGGGAGC prevent valproic acid-induced bone loss M Ghoneum,Signal transduction and targeted therapy,2024
Cervical vertebrae for early bone loss evaluation in osteoporosis mouse models B Teng,Quantitative imaging in medicine and surgery,2023
Identification and characterization of NFATc1+ skeletal stem cells in bone regeneration F Yu,Cell reports,2022
Peptide modified geniposidic acid targets bone and effectively promotes osteogenesis M Liu,Journal of Orthopaedic Translation,2022
Asiatic acid improves high-fat-diet-induced osteoporosis in mice via regulating SIRT1/FOXO1 signaling and inhibiting oxidative stress X Chen,Histology and histopathology,2022
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species Wenzheng Pan,Biochemical pharmacology,2021
Conditional Knockout of PDK1 in Osteoclasts Suppressed Osteoclastogenesis and Ameliorated Prostate Cancer-Induced Osteolysis Y Zhang,Researchsquare,2021
Mutations in Profilin 1 cause early-onset Paget's disease of bone with giant cell tumors Z Wei,Journal of Bone and Mineral Research,2021
Conditional knockout of the PDK‐1 gene in osteoblasts affects osteoblast differentiation and bone formation Y Bai,Journal of Cellular Physiology,2021
Acanthopanax senticosus aqueous extract ameliorates ovariectomy-induced bone loss in middle-aged mice by inhibiting the receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis H Xu,Food & Function,2020
Hydrogen sulfide protects against particle┸\induced inflammatory response and osteolysis via SIRT1 pathway in prosthesis loosening Liu L,FASEB,2020
The emerging role of IMD 0354 on bone homeostasis by suppressing osteoclastogenesis and bone resorption, but without affecting bone formation Chen W, et al,Cell Death and Disease,2019
A novel transgenic murine model with persistently brittle bones simulating osteogenesis imperfecta type I Yi Liu, et al,Bone,2019
Malt1 deficient mice develop osteoporosis independent of osteoclast-intrinsic effects of Malt1 deficiency Monajemi M, et al,Journal of Leukocyte Biology,2019
A novel anti-osteoporotic agent that protects against postmenopausal bone loss by regulating bone formation and bone resorption Yu-te Yang .et al,Life Sciences,2018
A Novel Diterpenoid Suppresses Osteoclastogenesis and Promotes Osteogenesis by Inhibiting Ifrd1-and IκBα-Mediated p65 Nuclear Translocation Xie, Zi\'ang.et al,Journal of Bone and Mineral Research ,2017
Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice Khorasani MS.et al,Arthritis Res Ther.,2015
Altered bone development in a mouse model of peripheral sensory nerve inactivation. Heffner MA et al,J Musculoskelet Neuronal Interact,2014

显示更多

收起更多

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.