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中文名称:小鼠免疫球蛋白G(IgG)酶联免疫试剂盒
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货号:CSB-E07980m
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规格:96T/48T
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价格:¥3200/¥2500
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其他:
产品详情
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产品描述:CUSABIO小鼠免疫球蛋白G(IgG)酶联免疫检测试剂盒(货号:CSB-E07980m),基于竞争法原理实现定量分析,适用于检测血清、血浆、细胞培养上清、尿液及组织匀浆等多种样本中的IgG含量。IgG是体液免疫的核心成分,在抗病原体感染、免疫调节及抗体依赖性细胞介导的细胞毒作用(ADCC)中发挥关键功能,其水平变化常用于评估免疫状态或炎症反应。本试剂盒检测范围为125 ng/mL至8000 ng/mL,采用竞争结合原理:样本中的IgG与酶标记的IgG竞争结合预包被抗体,通过底物显色后测定吸光度,信号强度与目标物浓度呈负相关,从而实现精准定量。该试剂盒具备高灵敏度和特异性,操作流程标准化,可满足科研领域对小鼠模型免疫指标的研究需求,例如疫苗效力评估、自身免疫性疾病机制探索、感染模型抗体动态监测,或生物制品生产过程中抗体表达水平的质量控制分析。
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别名:N/A
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缩写:IgG
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种属:Mus musculus (Mouse)
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样本类型:serum, plasma, cell culture supernates, urine, tissue homogenates
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检测范围:125 ng/mL-8000 ng/mL
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灵敏度:29 ng/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Immunology
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测定原理:quantitative
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测定方法:Competitive
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精密度:
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
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线性度:
To assess the linearity of the assay, samples were spiked with high concentrations of mouse IgG in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
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数据处理:
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货期:3-5 working days
引用文献
- Multi-omics analysis reveals the alleviating effects of Bifidobacterium infantis M-16V on food allergy through modulation of gut microbiota, metabolome, and gene expression in mice and infants N Li, Y Zhang, S Gao, Q Zhang, X Wang, W Cui, C Xu,Microbiome,2024
- Co‐Delivery of aPD‐L1 and CD73 Inhibitor Using Calcium Phosphate Nanoparticles for Enhanced Melanoma Immunotherapy with Reduced Toxicity P Liu, J Guo, Z Xie, Y Pan, B Wei, Y Peng,Advanced Science,2024
- TM9SF1 expression correlates with autoimmune disease activity and regulates antibody production through mTOR-dependent autophagy J Xiao, Z Zhao, F Zhou, J Xiong, Z Yang,BMC medicine,2024
- Immunoactivity-Enhancing Effect of Fermented Samultang Porridge in an Animal Model of Cyclophospahmide-Induced Immunodeficiency JH Oh,/,2023
- LncRNA IL21‐AS1 interacts with hnRNPU protein to promote IL21 overexpression and aberrant differentiation of Tfh cells in systemic lupus erythematosus L Liu,Clinical and translational medicine,2022
- Immunoregulatory activity of a low-molecular-weight heteropolysaccharide from Ganoderma leucocontextum fruiting bodies in vitro and in vivo X Gao,Food chemistry,2022
- The effects of EGb761 on lipopolysaccharide-induced depressive-like behaviour in C57BL/6J mice Yuehan Zhao, Yongdong Zhang, Fang Pan,Centr Eur J Immunol ,2015
相关产品
靶点详情
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最新研究进展:IgG (免疫球蛋白G) 是人体内最常见的抗体类型之一,由四个亚基组成,可与病原体和其他抗原结合以识别并清除它们。最近的研究表明,IgG不仅可以提供针对病原体的保护作用,还可以通过其Fc部分与细胞表面Fc受体结合并调节免疫反应,如促进细胞吞噬、激活T细胞等。 最新研究还发现,IgG可能在其他疾病中发挥重要作用,如自身免疫性疾病、癌症和神经系统疾病等。例如,在多发性硬化症中,IgG可能通过多种机制参与病理过程,包括炎症反应、神经损伤和再生等。此外,IgG还可能在肿瘤治疗中发挥作用,如通过激活免疫细胞攻击肿瘤细胞等。
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