ROCK2
ROCK2，即Rho相关卷曲螺旋激酶2，别名Rho激酶2。它是一种丝氨酸/苏氨酸蛋白激酶，分子量大约160 kD，属于Rho/ROCK信号通路的关键组成部分。ROCK2的作用机制主要通过磷酸化多种底物蛋白，参与细胞形态、运动、增殖和凋亡等生理过程的调控。ROCK2在肌肉收缩、细胞形态和迁移、细胞增殖和分化以及细胞凋亡等方面发挥重要作用。此外，ROCK2与多种疾病的发生发展有关，包括糖尿病肾病、肿瘤、高血压、神经损伤性疾病等，因此作为药物研发的靶点受到了广泛关注。
热销产品
ROCK2 Recombinant Monoclonal Antibody (CSB-RA152329A0HU)
验证数据
Western Blot
Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, L02 whole cell lysate, HepG2 whole cell lysate, Mouse Brain whole cell lysate, Rat Brain whole cell lysate
All lanes: ROCK2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 161 kDa
Observed band size: 161 kDa
Immunofluorescence staining of Hela Cells with CSB-RA152329A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Human Rho-associated coiled-coil containing protein kinase 2(Rock-2) ELISA Kit (CSB-E14993h)
验证数据
货号：CSB-E14993h
规格：96T/48T
灵敏度：7.8 pg/mL
检测范围：0.625 ng/mL-40 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
ROCK2 Antibodies
ROCK2 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA020059GA01HU | ROCK2 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA035451 | Phospho-ROCK2 (Tyr722) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA020059ESR1HU | ROCK2 Antibody | Human, Rat | ELISA, WB, IHC, IF |
| CSB-PA004018 | ROCK2 Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA005112 | ROCK2 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA242246 | ROCK2 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA081497 | ROCK2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA020059DA01HU | ROCK2 Antibody | Human, Mouse | ELISA, WB |
| CSB-PA020059DB01HU | ROCK2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA020059DC01HU | ROCK2 Antibody, FITC conjugated | Human | |
| CSB-PA020059DD01HU | ROCK2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA152329A0HU | ROCK2 Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, IF |
ROCK2 Proteins
ROCK2 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP020059MO CSB-EP020059MO CSB-BP020059MO CSB-MP020059MO CSB-EP020059MO-B |
Recombinant Mouse Rho-associated protein kinase 2 (Rock2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP020059HU CSB-EP020059HU CSB-BP020059HU CSB-MP020059HU CSB-EP020059HU-B |
Recombinant Human Rho-associated protein kinase 2 (ROCK2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP636705BO CSB-EP636705BO CSB-BP636705BO CSB-MP636705BO CSB-EP636705BO-B |
Recombinant Bovine Rho-associated protein kinase 2 (ROCK2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP720322RA CSB-EP720322RA CSB-BP720322RA CSB-MP720322RA CSB-EP720322RA-B |
Recombinant Rat Rho-associated protein kinase 2 (Rock2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ROCK2 ELISA Kit
ROCK2 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E14993h | Human Rho-associated coiled-coil containing protein kinase 2(Rock-2) ELISA Kit | serum, plasma, cell culture supernates | 7.8 pg/mL |
