GYS1
GYS1，即肌肉型糖原合酶。GYS1的活性受到多种因素的精细调控，特别是胰岛素信号通路的激活可以促进其磷酸化，进而提高酶的活性，加强糖原的合成。此外，GYS1还受到AMPK（AMP激活的蛋白激酶）等其他信号分子的影响，确保在能量需求变化时能够迅速调整糖原的合成速率。在生理学上，GYS1对于维持肌肉组织的能量储备、支持运动能力以及调节全身血糖水平都至关重要。当GYS1功能出现障碍时，可能会导致糖原积累异常，影响肌肉功能，甚至与某些代谢性疾病的发展有关，例如2型糖尿病。深入理解GYS1的作用机制及其在疾病中的角色，对于开发新的治疗方法具有重要意义。
热销产品
Phospho-GYS1 (S641) Recombinant Monoclonal Antibody (CSB-RA010078A641phHU)
验证数据
Western Blot
Positive WB detected in Hela whole cell lysate,HepG2 whole cell lysate(treated with Calyculin A or EGF)
All lanes Phospho-GYS1 antibody at 1.12μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 85 KDa
Observed band size: 85 KDa
Immunofluorescence staining of HepG2 cells with CSB-RA010078A641phHU at 1:100,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
GYS1 Antibodies
GYS1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA010078GA01HU | GYS1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA568101 | Phospho-GYS1 (Ser645) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA009060 | Phospho-GYS1 (S641) Antibody | Human,Mouse | WB, ELISA |
| CSB-PA009063 | Phospho-GYS1 (S645) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA009067 | GYS1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA009070 | GYS1 Antibody | Human,Mouse | WB, ELISA |
| CSB-PA985220 | GYS1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA170597 | GYS1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-RA010078A641phHU | Phospho-GYS1 (S641) Recombinant Monoclonal Antibody | Human | ELISA, WB, IF |
GYS1 Proteins
GYS1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP010078HU CSB-EP010078HU CSB-BP010078HU CSB-MP010078HU CSB-EP010078HU-B |
Recombinant Human Glycogen [starch] synthase, muscle (GYS1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GYS1 Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP010078RB CSB-EP010078RB CSB-BP010078RB CSB-MP010078RB CSB-EP010078RB-B |
Recombinant Rabbit Glycogen [starch] synthase, muscle (GYS1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GYS1 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP010078BO CSB-EP010078BO CSB-BP010078BO CSB-MP010078BO CSB-EP010078BO-B |
Recombinant Bovine Glycogen [starch] synthase, muscle (GYS1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GYS1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP383396RA CSB-EP383396RA CSB-BP383396RA CSB-MP383396RA CSB-EP383396RA-B |
Recombinant Rat Glycogen [starch] synthase, muscle (Gys1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GYS1 Proteins for Pongo abelii (Sumatran orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP722357PYX CSB-EP722357PYX CSB-BP722357PYX CSB-MP722357PYX CSB-EP722357PYX-B |
Recombinant Pongo abelii Glycogen [starch] synthase, muscle (GYS1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GYS1 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP818648MOW CSB-EP818648MOW CSB-BP818648MOW CSB-MP818648MOW CSB-EP818648MOW-B |
Recombinant Macaca mulatta Glycogen [starch] synthase, muscle (GYS1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
