CBLB
CBLB，即Casitas B淋巴瘤原癌基因B，别名Cbl-b、Nbla00127、RNF56。它来源于人类基因组，具体由CBLB基因编码。CBLB是一种RING型E3泛素连接酶，属于Cbl家族成员，在调节T细胞功能方面发挥核心作用。其作用机制是通过促进特定底物的泛素化，进而调控这些底物的降解或功能，从而负向调节免疫功能。在生物学上，CBLB的活性抑制可以增强抗肿瘤免疫效应，因为它能够减少肿瘤细胞通过高表达CBLB实现的免疫逃逸。因此，CBLB在癌症免疫治疗中具有重要的研究价值和应用前景。
热销产品
Recombinant Human E3 ubiquitin-protein ligase CBL-B (CBLB), partial
CSB-YP623789HU
来源：Yeast
CSB-EP623789HU
来源：E.coli
CSB-BP623789HU
来源：Baculovirus
CSB-MP623789HU
来源：Mammalian cell
CSB-EP623789HU-B
来源：In Vivo Biotinylation in E.coli
CBLB Antibodies
CBLB for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA004579GA01HU | CBLB Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IP |
CBLB Proteins
CBLB Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP623789HU CSB-EP623789HU CSB-BP623789HU CSB-MP623789HU CSB-EP623789HU-B |
Recombinant Human E3 ubiquitin-protein ligase CBL-B (CBLB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CBLB Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP667545MO CSB-EP667545MO CSB-BP667545MO CSB-MP667545MO CSB-EP667545MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase CBL-B (Cblb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CBLB Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP715671XBF CSB-EP715671XBF CSB-BP715671XBF CSB-MP715671XBF CSB-EP715671XBF-B |
Recombinant Xenopus tropicalis E3 ubiquitin-protein ligase CBL-B (cblb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CBLB Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP814329RA CSB-EP814329RA CSB-BP814329RA CSB-MP814329RA CSB-EP814329RA-B |
Recombinant Rat E3 ubiquitin-protein ligase CBL-B (Cblb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
