AGER
AGER，即高级糖基化终产物特异性受体，别名RAGE，是免疫球蛋白超家族成员，主要表达于细胞表面。作为跨膜信号转导受体，AGER与多种配体结合，通过激活NF-κ-B等信号通路，调控炎症细胞因子释放，参与细胞增殖、迁移及炎症反应。在生物学上，AGER与糖尿病并发症、神经退行性疾病及癌症等密切相关，其表达受炎症与氧化应激调控，是评估疾病严重程度及预后的潜在生物标志物。针对AGER的靶向治疗，如小分子抑制剂或抗体疗法，有望为相关疾病提供新的治疗策略。
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验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
验证数据
The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA066696(AGER Antibody) at dilution 1/70. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA066696(AGER Antibody) at dilution 1/70. (Original magnification: ×200)
Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA066696(AGER Antibody) at dilution 1/750 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 2 minutes
AGER Antibodies
AGER for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA14209B0Rb | AGER Antibody, HRP conjugated | Human | ELISA |
| CSB-PA14209A0Rb | AGER Antibody | Human | ELISA, IHC, IF |
| CSB-PA007810 | AGER Antibody | Human | WB, IHC, ELISA |
| CSB-PA066696 | AGER Antibody | Human | ELISA,WB,IHC |
| CSB-PA874417 | AGER Antibody | Human | ELISA,WB,IHC |
AGER Proteins
AGER Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001441MO CSB-EP001441MO CSB-BP001441MO CSB-MP001441MO CSB-EP001441MO-B |
Recombinant Mouse Advanced glycosylation end product-specific receptor (Ager), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AGER Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001441RA CSB-EP001441RA CSB-BP001441RA CSB-MP001441RA CSB-EP001441RA-B |
Recombinant Rat Advanced glycosylation end product-specific receptor (Ager), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AGER Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001441HU CSB-EP001441HU CSB-BP001441HU CSB-MP001441HU CSB-EP001441HU-B |
Recombinant Human Advanced glycosylation end product-specific receptor (AGER), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP001441HU | Recombinant Human Advanced glycosylation end product-specific receptor (AGER), partial | E.coli |
| CSB-MP001441HU1c7 | Recombinant Human Advanced glycosylation end product-specific receptor (AGER), partial | Mammalian cell |
AGER Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001441BO CSB-EP001441BO CSB-BP001441BO CSB-MP001441BO CSB-EP001441BO-B |
Recombinant Bovine Advanced glycosylation end product-specific receptor (AGER), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AGER ELISA Kit
AGER ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E09354h | Human Receptor for advanced glycation end products, RAGE/AGER ELISA Kit | serum, plasma, tissue homogenates | 19.5 pg/mL |
| CSB-E09354h-IS | Human Receptor for advanced glycation end products, RAGE/AGER ELISA Kit | serum, plasma, tissue homogenates | 19.5 pg/mL |
AGER ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL001441MO | Mouse Advanced glycosylation end product-specific receptor(AGER) ELISA kit | serum, plasma, tissue homogenates | 0.078 ng/ml |
AGER ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL001441RA | Rat Advanced glycosylation end product-specific receptor(AGER) ELISA kit | serum, plasma,tissue homogenates | 7.81 pg/mL |
