Recombinant Danio rerio Dynamin-like 120 kDa protein, mitochondrial (opa1)

in vitro E.coli expression system

中文名称：

斑马鱼opa1重组蛋白
货号：

CSB-CF722610DIL
规格：
来源：

in vitro E.coli expression system
其他：

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基因名：

opa1
Uniprot No.：

Q5U3A7
别名：

opa1; zgc:92092; Dynamin-like 120 kDa protein, mitochondrial; Optic atrophy protein 1 homolog
种属：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白长度：

Full Length of Mature Protein
表达区域：

194-966
氨基酸序列

APDVPPASAAMADSGDKQFKKSSDKEKVDQLQEELLRTQLKYQRMLERLEKENKELRKVV LQKDDKGIHQRKVKKSLIDMYSEVLDILSDYDSNYNTQDHLPRVVVVGDQSAGKTSVLEM IAQARIFPRGSGEMMTRSPVKVTLSEGPHHVAMFKDSSREFDLGKEEDLAALRHEIELRM RKSVKEGQTVSPETISLSVKGPGIQRMVLVDLPGVISTVTTGMAADTKETIFSISKAYMQ NPNAIILCIQDGSVDAERSIVTDLVSQMDPQGKRTIFVLTKVDLAEKNLASPSRIQQIVE GKLFPMKALGYFAVVTGKGSPNESIDSIKDYEEDFFQNSRLLKDGMLKAHQVTTKNLSLA VSDCFWKMVRESVEQQADAFKASRFNLETEWKNNYPRLRELDRNELYEKAKNEILDEVIS LSQVTPKHWESILQKKLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPH KALEVAWETLQEEFARFMAEYKGKDQDDIFDKLKEAVKDESIKRHKWNERAMDSLRVIQH NALEDRSITDKPQWDAAIQFMEETLQSRLKDTESVIADMVGPDWKQRWMSWKNRTPEQHT RNETKNELERLLKLHEDHTAYLANDEVTTVRKNLEARGVEVDPVLIKDTWHQLFRRHFLQ KALLHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLGITANTLRQQLTNTEVRRLE KNVKEVLEDFGEDNEKKVQLITGRRVQLAEDLKKVREIQEKLEAFIEALHKEK
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

N-terminal 10xHis-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

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功能：

Dynamin-related GTPase that is essential for normal mitochondrial morphology by regulating the equilibrium between mitochondrial fusion and mitochondrial fission. Binds lipid membranes enriched in negatively charged phospholipids, such as cardiolipin, and promotes membrane tubulation. The intrinsic GTPase activity is low, and is strongly increased by interaction with lipid membranes. Plays a role in remodeling cristae and the release of cytochrome c during apoptosis.; Inactive form produced by cleavage at S1 position by oma1 following stress conditions that induce loss of mitochondrial membrane potential, leading to negative regulation of mitochondrial fusion.
基因功能参考文献：
1. Opa1 is required for proper mitochondrial metabolism in early development PMID: 23516612
亚细胞定位：

Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space. Mitochondrion membrane.
蛋白家族：

TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
数据库链接：

KEGG: dre:492332

STRING: 7955.ENSDARP00000095031

UniGene: Dr.37656

Recombinant Danio rerio Dynamin-like 120 kDa protein, mitochondrial (opa1)

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