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  4. Recombinant Rat ELKS/Rab6-interacting/CAST family member 1 (Erc1), partial

Recombinant Rat ELKS/Rab6-interacting/CAST family member 1 (Erc1), partial

  • 中文名称：
    大鼠Erc1重组蛋白
  • 货号：
    CSB-YP007767RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Erc1重组蛋白
  • 货号：
    CSB-EP007767RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Erc1重组蛋白
  • 货号：
    CSB-EP007767RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Erc1重组蛋白
  • 货号：
    CSB-BP007767RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Erc1重组蛋白
  • 货号：
    CSB-MP007767RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Erc1
  • Uniprot No.：
    Q811U3
  • 别名：
    Erc1; Cast2; Elks; Rab6ip2; ELKS/Rab6-interacting/CAST family member 1; ERC-1; CAZ-associated structural protein 2; CAST2; Rab6-interacting protein 2
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport.
  • 基因功能参考文献：
    1. new component of the cytomatrix at the active zone (CAZ) and, together with CAST1, may be involved in the formation of the CAZ structure [CAST2] PMID: 14723704
    2. ELKS is involved in Ca(2+)-dependent exocytosis from PC12 cells PMID: 16716196
    3. ELKS positively regulates exocytotic release in RBL-2H3 by acting on the plasma membrane upon stimulation. PMID: 19515363
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic active zone.
  • 组织特异性：
    Isoform 1 is specifically expressed in brain. A further probable isoform is widely expressed outside of brain It is referred to as ERC1a by PubMed:12391317 and characterized by a C-terminus identical to that of isoforms 1 in human and mouse.
  • 数据库链接：

    KEGG: rno:266806

    STRING: 10116.ENSRNOP00000012397

    UniGene: Rn.207836

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