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  4. Recombinant Rat ATP-binding cassette sub-family A member 7 (Abca7), partial

Recombinant Rat ATP-binding cassette sub-family A member 7 (Abca7), partial

  • 中文名称：
    Recombinant Rat ATP-binding cassette sub-family A member 7(Abca7) ,partial
  • 货号：
    CSB-YP763167RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat ATP-binding cassette sub-family A member 7(Abca7) ,partial
  • 货号：
    CSB-EP763167RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat ATP-binding cassette sub-family A member 7(Abca7) ,partial
  • 货号：
    CSB-EP763167RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat ATP-binding cassette sub-family A member 7(Abca7) ,partial
  • 货号：
    CSB-BP763167RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat ATP-binding cassette sub-family A member 7(Abca7) ,partial
  • 货号：
    CSB-MP763167RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Abca7
  • Uniprot No.：
    Q7TNJ2
  • 别名：
    Abca7ATP-binding cassette sub-family A member 7
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocyte differentiation. Involved in lipid raft organization and CD1D localization on thymocytes and antigen-presenting cells, which plays an important role in natural killer T-cell development and activation. Plays a role in phagocytosis of apoptotic cells by macrophages. Macrophage phagocytosis is stimulated by APOA1 or APOA2, probably by stabilization of ABCA7. Also involved in phagocytic clearance of amyloid-beta by microglia cells and macrophages. Further limits amyloid-beta production by playing a role in the regulation of amyloid-beta A4 precursor protein (APP) endocytosis and/or processing.
  • 基因功能参考文献：
    1. rat ABCA7 is preferentially expressed in platelets and that its apparent molecular mass is 250kDa PMID: 12727224
    2. Data show that rat ABCA7 is preferentially expressed in platelets and that its apparent molecular mass is 250kDa. PMID: 12727224
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Cell projection, ruffle membrane. Cell projection, phagocytic cup. Cytoplasm.
  • 蛋白家族：
    ABC transporter superfamily, ABCA family
  • 组织特异性：
    Expressed in blood cells. Also detected in brain and ovary tissues (at protein level). Expressed in platelet.
  • 数据库链接：

    KEGG: rno:299609

    STRING: 10116.ENSRNOP00000063805

    UniGene: Rn.25281

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