Recombinant Mouse Lymphocyte antigen 6K (Ly6k)

中文名称：

小鼠Ly6k重组蛋白
货号：

CSB-YP861475MO
规格：

￥2616
图片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

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纯度：

Greater than 85% as determined by SDS-PAGE.
基因名：

Ly6k
Uniprot No.：

Q9CWP4
别名：

Ly6k; Lymphocyte antigen 6K; Ly-6K
种属：

Mus musculus (Mouse)
蛋白长度：

Full Length of Mature Protein
来源：

Yeast
分子量：

13.1 kDa
表达区域：

21-123aa
氨基酸序列

LTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPG
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

C-terminal 6xHis-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

25-35 business days
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

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功能：

Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida. May play a role in cell growth.
基因功能参考文献：
1. Study demonstrated that both TEX101 and Ly6k contribute mutually for their protein expression in the testicular germ cells, suggesting that the expression-balance of these two proteins is essential for fertile sperm formation. PMID: 27005865
2. LY6K is a newly identified factor involved in sperm fertilizing ability PMID: 24501175
3. This information is essential for the molecular classification of Ly6k, and may help uncover the detailed physiological role of Ly6k in gametogenesis, or cancer biology. PMID: 20920470
4. Expression profiling confirmed that mLy-6K is expressed by plasma cells but not B cells or tissues not containing plasma cells. PMID: 18372042
5. This study confirmed the biological interaction between TEX101 and Ly6k. PMID: 18503752
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亚细胞定位：

Secreted. Cytoplasm. Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasmic vesicle, secretory vesicle, acrosome. Membrane raft.
组织特异性：

Strongly expressed in testes and weakly expressed in the epididymis, ovary, and uterus. Expressed in testicular germ cells (TGCs). Expressed in the testicular seminiferous tubules, in spermatocytes, spermatids, and testicular spermatozoa.
数据库链接：

KEGG: mmu:76486

STRING: 10090.ENSMUSP00000052599

UniGene: Mm.273319

Recombinant Mouse Lymphocyte antigen 6K (Ly6k)

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