Recombinant Macaca fascicularis Delta-like protein 3 (DLL3), partial (Active)

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中文名称：

猕猴DLL3重组蛋白
货号：

CSB-MP3536MOV
规格：

￥1140
图片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized DLL3 at 2 μg/ml can bind Anti-DLL3 Recombinant Antibody（CSB-RA882142A1HU）, the EC₅₀ is 1.625-2.702 ng/mL. Biological Activity Assay
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纯度：

Greater than 85% as determined by SDS-PAGE.
内毒素：

Less than 1.0 EU/ug as determined by LAL method.
生物活性：

Measured by its binding ability in a functional ELISA. Immobilized DLL3 at 2 μg/mL can bind Anti-DLL3 Recombinant Antibody（CSB-RA882142A1HU）, the EC₅₀ is 1.625-2.702 ng/mL.
基因名：

DLL3
Uniprot No.：

A0A2K5WSR4
分子结构：
种属：

Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
蛋白长度：

Partial
来源：

Mammalian cell
分子量：

50.6 kDa
表达区域：

27-490aa
氨基酸序列

AGVFELQIHSFGPGPGPGAPRSPCSARGPCRLFFRVCLKPGLSEEAAESPCALGAALSARGPVYTEQPEAPAPDLPLPNGLLQVPFRDAWPGTFSLIIETWREELGDQIGGPAWSLLARVTRRRRLAAGGPWARDIQRAGAWELRFSYRARCELPAVGTACTRLCRPRSAPSRCGPGLRPCAPLEDECEAPPVCRAGCSLEHGFCEQPGECRCLEGWTGPLCMVPVSTSSCLGLRGPSSTTTGCLVPGPGPCDGNPCANGGSCSETPGSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRNCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGVSALPAAPPGLRPGDPQR
蛋白标签：

C-terminal 6xHis-tagged
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

3-7 business days
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
产品描述：

CUSABIO's product CSB-MP3536MOV is an active recombinant Delta-like protein 3 (DLL3) tagged the 6xHis at the C-terminus. It is expressed in mammalian cells with the gene fragment mapping within amino acids 27-490 of Macaca fascicularis DLL3 protein. Its bioactivity has been validated by binding to the anti-DLL3 antibody in a functional ELISA. The EC50 is 1.625-2.702 ng/mL. Its purity is over 82% measured by SDS-PAGE. On the gel, this protein migrated to the molecular weight band of approximately 55 kDa. The endotoxin content of the recombinant protein was less than 1.0 EU/ug determined by the LAL method. This DLL3 protein is available. DLL3 is a negative Notch regulator and is expressed during brain development where it modulates somitogenesis. It is not expressed on the surface of normal cells but is highly expressed on the surface of tumor cells. Aberrant DLL3 expression has been found in most small cell lung cancer (SCLC) cells.
Datasheet & COA：

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Recombinant Macaca fascicularis Delta-like protein 3 (DLL3), partial (Active)

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