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  4. Recombinant Mouse Histone H1.0 (H1f0)

Recombinant Mouse Histone H1.0 (H1f0)

  • 中文名称：
    小鼠H1f0重组蛋白
  • 货号：
    CSB-YP010087MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠H1f0重组蛋白
  • 货号：
    CSB-EP010087MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠H1f0重组蛋白
  • 货号：
    CSB-EP010087MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠H1f0重组蛋白
  • 货号：
    CSB-BP010087MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠H1f0重组蛋白
  • 货号：
    CSB-MP010087MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    H1f0
  • Uniprot No.：
    P10922
  • 别名：
    H1-0; H1f0; H1fv; Histone H1.0; Histone H1'; Histone H1(0); MyD196) [Cleaved into: Histone H1.0; N-terminally processed]
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-194
  • 氨基酸序列
    MTENSTSAPA AKPKRAKASK KSTDHPKYSD MIVAAIQAEK NRAGSSRQSI QKYIKSHYKV GENADSQIKL SIKRLVTTGV LKQTKGVGAS GSFRLAKGDE PKRSVAFKKT KKEVKKVATP KKAAKPKKAA SKAPSKKPKA TPVKKAKKKP AATPKKAKKP KVVKVKPVKA SKPKKAKTVK PKAKSSAKRA SKKK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
  • 基因功能参考文献：
    1. Marked reduction in total H1 levels causes significant reduction in both expression and the level of active histone mark H3K4me3 at many Hox genes. PMID: 22701719
    2. both P-TEFb activity and H1 phosphorylation are necessary for the full differentiation of C2C12 myoblasts into myotubes. PMID: 21503884
    3. Histone H1 poly[ADP]-ribosylation of proteins over a specific time course is required for the changes in synaptic plasticity related to memory stabilization in mice. PMID: 20926656
    4. H1 dephosphorylation and H2A.X hyperphosphorylation are necessary steps on the apoptotic pathway. PMID: 11803372
    5. Analysis of DNA-induced secondary structure of the carboxyl-terminal domain of histone H1 subtypes H1(0)(C-H1(0)) and H1t (C-H1t). PMID: 16006555

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  • 亚细胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    Histone H1/H5 family
  • 数据库链接：

    KEGG: mmu:14958

    STRING: 10090.ENSMUSP00000137309

    UniGene: Mm.24350

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