Recombinant Mouse Dedicator of cytokinesis protein 7 (Dock7), partial

中文名称：

小鼠Dock7重组蛋白
货号：

CSB-YP823155MO
规格：
来源：

Yeast
其他：

中文名称：

小鼠Dock7重组蛋白
货号：

CSB-EP823155MO
规格：
来源：

E.coli
其他：

中文名称：

小鼠Dock7重组蛋白
货号：

CSB-EP823155MO-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

小鼠Dock7重组蛋白
货号：

CSB-BP823155MO
规格：
来源：

Baculovirus
其他：

中文名称：

小鼠Dock7重组蛋白
货号：

CSB-MP823155MO
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

Dock7
Uniprot No.：

Q8R1A4
别名：

Dock7; Gm430; Kiaa1771; MnltDedicator of cytokinesis protein 7; Protein moonlight
种属：

Mus musculus (Mouse)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization. As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton. Has a role in pigmentation. Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3.
相关疾病：

Defects in Dock7 are responsible for the moonlight phenotype (mnlt). mnlt/mnlt mice display an overall lightened coat color and hypopigmentation of the belly and distal extremities, particularly the paws, tail tip, and genitalia.
亚细胞定位：

Cell projection, axon.
蛋白家族：

DOCK family
数据库链接：

STRING: 10090.ENSMUSP00000075233

UniGene: Mm.260623

Recombinant Mouse Dedicator of cytokinesis protein 7 (Dock7), partial

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