Recombinant Human Nuclear pore complex protein Nup93 (NUP93), partial

中文名称：

人NUP93重组蛋白
货号：

CSB-YP822683HU
规格：
来源：

Yeast
其他：

中文名称：

人NUP93重组蛋白
货号：

CSB-EP822683HU
规格：
来源：

E.coli
其他：

中文名称：

人NUP93重组蛋白
货号：

CSB-EP822683HU-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

人NUP93重组蛋白
货号：

CSB-BP822683HU
规格：
来源：

Baculovirus
其他：

中文名称：

人NUP93重组蛋白
货号：

CSB-MP822683HU
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

NUP93
Uniprot No.：

Q8N1F7
别名：

NUP93; KIAA0095Nuclear pore complex protein Nup93; 93 kDa nucleoporin; Nucleoporin Nup93
种属：

Homo sapiens (Human)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.
基因功能参考文献：
1. we show that knockdown of Nup188 or its binding partner Nup93 leads to a loss of cilia during embryonic development while leaving NPC function largely intact. Many data, including the localization of endogenous Nup188/93 at cilia bases, support their direct role at cilia. Super-resolution imaging of Nup188 shows two barrel-like structures PMID: 27593162
2. NUP93 and exportin 5 interact with the signaling protein SMAD4 and that NUP93 mutations abrogated interaction with SMAD4 PMID: 26878725
3. Caspases target only Nup93 and Nup96 within the core structure of the nuclear pore complex PMID: 16286466
相关疾病：

Nephrotic syndrome 12 (NPHS12)
亚细胞定位：

Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Nucleus envelope.
蛋白家族：

Nucleoporin interacting component (NIC) family
数据库链接：

HGNC: 28958

OMIM: 614351

KEGG: hsa:9688

STRING: 9606.ENSP00000310668

UniGene: Hs.276878

Recombinant Human Nuclear pore complex protein Nup93 (NUP93), partial

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