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  4. Recombinant Human Histone deacetylase complex subunit SAP130 (SAP130), partial

Recombinant Human Histone deacetylase complex subunit SAP130 (SAP130), partial

  • 中文名称：
    人SAP130重组蛋白
  • 货号：
    CSB-YP887944HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SAP130重组蛋白
  • 货号：
    CSB-EP887944HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SAP130重组蛋白
  • 货号：
    CSB-EP887944HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SAP130重组蛋白
  • 货号：
    CSB-BP887944HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SAP130重组蛋白
  • 货号：
    CSB-MP887944HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SAP130
  • Uniprot No.：
    Q9H0E3
  • 别名：
    130 kDa Sin3-associated polypeptide; FLJ12761; Histone deacetylase complex subunit SAP130; mSin3A associated protein 130; Sap130; Sin3-associated polypeptide p130; Sin3A associated protein 130kDa; Sin3A associated protein; SP130_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 产品描述：
    Recombinant Human Histone deacetylase complex subunit SAP130 (SAP130) is a partial length protein expressed with an N-terminal His-tagged or Tag-Free. Its purity was determined by SDS-PAGE and reached up to 85%. The activity of this protein isn’t tested. This recombinant SAP130 protein may be used to synthesize antibodies against SAP130 or on the studies of SAP130-associated signal transduction.
    SAP130 is a subunit of the histone deacetylase-dependent SIN3A corepressor complex, belonging to SAP130 family. It is mainly expressed in various cancer cell lines. This protein is located in nucleus and acts as a transcriptional repressor. SAP130 may function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
  • Datasheet ：
    Please contact us to get it.

产品评价

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SAP130 antibodies

靶点详情

  • 功能：
    Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
  • 基因功能参考文献：
    1. the TGFbeta pathway activation leads to recruitment of a KLF14-mSin3A-HDAC2 repressor complex to the TGFbetaRII promoter, as well as the remodeling of chromatin to increase histone marks that associate with transcriptional silencing. PMID: 19088080
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    SAP130 family
  • 组织特异性：
    Expressed in various cancer cell ines.
  • 数据库链接：

    HGNC: 29813

    OMIM: 609697

    KEGG: hsa:79595

    STRING: 9606.ENSP00000350333

    UniGene: Hs.32995

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