SAP130 Antibody

产品详情

Uniprot No.：

Q9H0E3
基因名：

SAP130
别名：

130 kDa Sin3-associated polypeptide antibody; FLJ12761 antibody; Histone deacetylase complex subunit SAP130 antibody; mSin3A associated protein 130 antibody; Sap130 antibody; Sin3-associated polypeptide p130 antibody; Sin3A associated protein 130kDa antibody; Sin3A associated protein antibody; SP130_HUMAN antibody
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Human SAP130
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
基因功能参考文献：
1. the TGFbeta pathway activation leads to recruitment of a KLF14-mSin3A-HDAC2 repressor complex to the TGFbetaRII promoter, as well as the remodeling of chromatin to increase histone marks that associate with transcriptional silencing. PMID: 19088080
亚细胞定位：

Nucleus.
蛋白家族：

SAP130 family
组织特异性：

Expressed in various cancer cell ines.
数据库链接：

HGNC: 29813

OMIM: 609697

KEGG: hsa:79595

STRING: 9606.ENSP00000350333

UniGene: Hs.32995