Recombinant Human GPI ethanolamine phosphate transferase 3 (PIGO), partial

中文名称：

人PIGO重组蛋白
货号：

CSB-YP855068HU
规格：
来源：

Yeast
其他：

中文名称：

人PIGO重组蛋白
货号：

CSB-EP855068HU
规格：
来源：

E.coli
其他：

中文名称：

人PIGO重组蛋白
货号：

CSB-EP855068HU-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

人PIGO重组蛋白
货号：

CSB-BP855068HU
规格：
来源：

Baculovirus
其他：

中文名称：

人PIGO重组蛋白
货号：

CSB-MP855068HU
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

PIGO
Uniprot No.：

Q8TEQ8
别名：

PIGO; UNQ632/PRO1249; GPI ethanolamine phosphate transferase 3; EC 2.-.-.-; Phosphatidylinositol-glycan biosynthesis class O protein; PIG-O
种属：

Homo sapiens (Human)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond.
基因功能参考文献：
1. PIGO deficiency shows variable phenotypes from infantile lethality to mild learning difficulties PMID: 28337824
2. Disease associated PIGO missense mutations resulted in decreased activity in vitro. PMID: 28327575
3. Novel PIGO mutations expand the clinical spectrum of PIGO abnormalities to include epileptic encephalopathy with mild elevation of alkaline phosphatase (ALP). PMID: 24417746
4. Our data identify PIGO as the second gene associated with HPMRS and suggest that a deficiency in GPI-anchor synthesis is the underlying molecular pathomechanism of HPMRS. PMID: 22683086
相关疾病：

Hyperphosphatasia with mental retardation syndrome 2 (HPMRS2)
亚细胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

PIGG/PIGN/PIGO family, PIGO subfamily
数据库链接：

HGNC: 23215

OMIM: 614730

KEGG: hsa:84720

STRING: 9606.ENSP00000339382

UniGene: Hs.522099

Recombinant Human GPI ethanolamine phosphate transferase 3 (PIGO), partial

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