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  4. Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1), partial

Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1), partial

  • 中文名称：
    人PLCH1重组蛋白
  • 货号：
    CSB-YP679884HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PLCH1重组蛋白
  • 货号：
    CSB-EP679884HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PLCH1重组蛋白
  • 货号：
    CSB-EP679884HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PLCH1重组蛋白
  • 货号：
    CSB-BP679884HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PLCH1重组蛋白
  • 货号：
    CSB-MP679884HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PLCH1
  • Uniprot No.：
    Q4KWH8
  • 别名：
    1-phosphatidylinositol 4; 1-phosphatidylinositol-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1; 5-bisphosphate phosphodiesterase eta-1; DKFZp434C1372; KIAA1069; MGC117152; Phosphoinositide phospholipase C-eta-1; Phospholipase C-eta-1; Phospholipase C-like protein 3; PLC-eta-1; PLC-L3; PLCeta1; Plch1; PLCH1_HUMAN; PLCL3
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

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PLCH1 antibodies

靶点详情

  • 功能：
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes.
  • 基因功能参考文献：
    1. High fertilization (56.06%) and pregnancy (41.7%) rates accomplished in this study following ICSI-AOA indicated that expression profiles of PLCzeta, PAWP, and TR-KIT were low in globozoospermic individuals PMID: 27089467
    2. A molecular model of the PLCeta2 EF-hand domain, constructed based upon the structure of calmodulin, suggested both EF-loops may participate in Ca(2+) -binding. PMID: 24123053
    3. The PLCH1 rs181696 single-nucleotide polymorphism was strongly associated with an increased risk of squamous cell carcinoma. PMID: 22658813
    4. molecular cloning of PLC-eta1 and PLC-eta2 PMID: 15583837
    5. The identification of a novel PLC isoform in the brains of human and mouse, named PLC-eta, which contains the conserved pleckstrin homology domain, X and Y domains for catalytic activity and the C2 domain. PMID: 15702972

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  • 亚细胞定位：
    Cytoplasm. Membrane.
  • 组织特异性：
    Expressed in brain and to a lower extent in lung. In brain, it is found in cerebrum, cerebellum and spinal cord.
  • 数据库链接：

    HGNC: 29185

    OMIM: 612835

    KEGG: hsa:23007

    STRING: 9606.ENSP00000345988

    UniGene: Hs.567423

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