Recombinant Danio rerio Protein DVR-1 (dvr1)

中文名称：

Recombinant Danio rerio Protein DVR-1 (dvr1)
货号：

CSB-EP330463DIL
规格：

￥2328
图片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

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纯度：

Greater than 90% as determined by SDS-PAGE.
生物活性：

Not Test
基因名：

dvr1
Uniprot No.：

P35621
别名：

dvr-1, vg1
种属：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白长度：

Full Length of Mature Protein
来源：

E.coli
分子量：

20.0 kDa
表达区域：

241-355aa
氨基酸序列

SASYYLPVTPSNVCKPRRLYIDFKDVGWQDWIIAPQGYLANYCHGECPFPLSESLNGTNHAILQTLVHSFDPKGTPQPCCVPIKLSPISMLYYDNNDNVVLRHYEDMVVDECGCR
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

C-terminal 6xHis-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Datasheet & COA：

Please contact us to get it.

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功能：

Serves to facilitate the differentiation of either mesoderm or endoderm either as a cofactor in an instructive signal or by providing permissive environment.
基因功能参考文献：
1. Together, these findings demonstrate that Gdf3 is an essential cofactor of Nodal signaling during establishment of the embryonic axis. PMID: 29140249
2. Collectively, these data indicate that gdf3 is critical for robust Nodal signaling at multiple stages in zebrafish embryonic development. PMID: 29140250
3. Dvr1 acts as a direct and essential mediator for convergence and extension cell movements during zebrafish gastrulation. PMID: 24892953
4. Dvr1 is responsible for enabling the transfer of a left-right signal from Kupffer's vesicle to lateral plate mesoderm. PMID: 23791819
5. serum Vg in zebrafish D. rerio is an acute phase protein with bacterial-binding and inhibiting activities. PMID: 20006406
6. Vg1 signaling in zebrafish depends on EGF-CFC proteins, but not on Nodal signals. Vg1 binds to and signal through Activin receptors only in the presence of EGF-CFC proteins. PMID: 12514096
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亚细胞定位：

Secreted.
蛋白家族：

TGF-beta family
组织特异性：

Abundant in ovaries and eggs, and equally distributed among all blastomeres.
数据库链接：

KEGG: dre:30125

STRING: 7955.ENSDARP00000055378

UniGene: Dr.307

Recombinant Danio rerio Protein DVR-1 (dvr1)

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