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  4. Recombinant Chicken 72 kDa type IV collagenase (MMP2), partial

Recombinant Chicken 72 kDa type IV collagenase (MMP2), partial

  • 中文名称：
    鸡MMP2重组蛋白
  • 货号：
    CSB-YP852663CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡MMP2重组蛋白
  • 货号：
    CSB-EP852663CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡MMP2重组蛋白
  • 货号：
    CSB-EP852663CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡MMP2重组蛋白
  • 货号：
    CSB-BP852663CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡MMP2重组蛋白
  • 货号：
    CSB-MP852663CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MMP2
  • Uniprot No.：
    Q90611
  • 别名：
    MMP2; 72 kDa type IV collagenase; EC 3.4.24.24; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Enhanced MMP-2, MMP-9 and TNF-alpha production in progressive phase correlated with sciatic nerve pathology in C. jejuni-induced Guillain-Barre syndrome in chicken model. PMID: 28916318
    2. Type I collagen promotes the expression and activation of MMPs in a lens epithelial cell-specific manner. PMID: 24400880
    3. Matrix metalloproteinase 2 (MMP2) was identified in chicken bile. Chickens fed gelatin supplements showed higher levels of bile MMP expression. Bile MMP may be associated with digestion of collagens and other extracellular matrix proteins in avian diets. PMID: 24879699
    4. The results obtained using the shell gland explants model indicate that dioxins and PCBs have a direct effect on the chicken oviduct, especially the shell gland, by affecting the expression of genes involved in the function of this oviductal segment. PMID: 24279180
    5. The results obtained indicate that in the chicken ovary MMP-2 may take part in the extracellular matrix remodelling required for follicle growth, development and regression. PMID: 23342920
    6. Endothelin-1-induced proliferation of chicken pulmonary artery smooth muscle cells (PA-SMCs) was concomitant with increased pro- and active matrix metalloproteinase (MMP)-2 production. However, PA-SMC proliferation was inhibited by two MMP inhibitors. PMID: 22377328
    7. From buds to follicles: matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis PMID: 21497985
    8. At the seven-somite stage, MMP-2/Ilomastat inhibition caused a shift in normal left-right patterning of cell proliferation PMID: 15844197
    9. It is suggested that MMP-2 and MMP-9 enzymes might play a role in the permeability increase of vessel walls by the destruction of the basement membranes in the salt-induced experimental ascites syndrome in broiler chickens PMID: 16537168
    10. functional role of MMP-2 in chondrogenesis of leg bud mesenchymal cells PMID: 17604018
    11. MMP-2 is related to chondrocyte differentiation and may be involved in cartilage remodeling in the avian growth plate PMID: 18344292
    12. MMP-2/MT3-MMP are involved in the initiation and progression of fibril growth, matrix assembly, and tendon development. PMID: 19221802

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  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Peptidase M10A family
  • 组织特异性：
    Produced by normal skin fibroblasts.
  • 数据库链接：

    KEGG: gga:386583

    STRING: 9031.ENSGALP00000005656

    UniGene: Gga.3199

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