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TTYH1 Antibody

文献引用 (2) 说明书
  • 中文名称：
    TTYH1兔多克隆抗体
  • 货号：
    CSB-PA867139LA01HU
  • 规格：
    ￥440
  • 图片：
    • Western Blot
      Positive WB detected in: Raji whole cell lysate(20µg), Hela whole cell lysate(20µg), HepG2 whole cell lysate(20µg), Mouse Brain tissue lysate(20µg)
      All lanes: TTYH1 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 50, 27,36 kDa
      Observed band size: 50 kDa
      Exposure time：120s
    • Immunofluorescence staining of Hela cell with CSB-PA867139LA01HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunofluorescence staining of Hela cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TTYH1 Polyclonal antibody
  • Uniprot No.：
    Q9H313
  • 基因名：
    TTYH1
  • 别名：
    TTYH1; Protein tweety homolog 1; hTTY1
  • 宿主：
    Rabbit
  • 反应种属：
    Human,mouse
  • 免疫原：
    Synthesized peptide derived from human TTYH1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TTYH1 Antibody (CSB-PA867139LA01HU)，的标记方式是Non-conjugated。对于TTYH1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA867139LB01HU TTYH1 Antibody, HRP conjugated ELISA
    FITC CSB-PA867139LC01HU TTYH1 Antibody, FITC conjugated
    Biotin CSB-PA867139LD01HU TTYH1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:1000
    IF 1:20-1:50
  • Protocols：
    ELISA Protocol
    Western Blotting (WB) Protocol
    Immunofluorescence (IF) Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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TTYH1 antibodies

TTYH1 Proteins

靶点详情

  • 功能：
    Probable chloride channel. May be involved in cell adhesion.; Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume.
  • 基因功能参考文献：
    1. In this report, we identify tweety-homolog 1 (Ttyh1), a membrane protein linked to neuronal development, as a potent driver of tumor microtube (TM)-mediated brain colonization by glioma cells. PMID: 28607172
    2. TTYH1 was not expressed in either the malignant or the control samples PMID: 25182704
    3. Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor. PMID: 24316981
    4. Nedd4-2 differentially interacts with and regulates TTYH1-3 PMID: 18577513
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Tweety family
  • 组织特异性：
    Expressed in brain, eye, ovary and testis, and at lower levels in muscle, placenta, liver and lung.
  • 数据库链接：

    HGNC: 13476

    OMIM: 605784

    KEGG: hsa:57348

    UniGene: Hs.268728

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