TTYH1 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TTYH1 Polyclonal antibody
Uniprot No.：

Q9H313
基因名：

TTYH1
别名：

TTYH1; Protein tweety homolog 1; hTTY1
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Protein tweety homolog 1 protein (50-178AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable chloride channel. May be involved in cell adhesion.; Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume.
基因功能参考文献：
1. In this report, we identify tweety-homolog 1 (Ttyh1), a membrane protein linked to neuronal development, as a potent driver of tumor microtube (TM)-mediated brain colonization by glioma cells. PMID: 28607172
2. TTYH1 was not expressed in either the malignant or the control samples PMID: 25182704
3. Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor. PMID: 24316981
4. Nedd4-2 differentially interacts with and regulates TTYH1-3 PMID: 18577513
亚细胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Tweety family
组织特异性：

Expressed in brain, eye, ovary and testis, and at lower levels in muscle, placenta, liver and lung.
数据库链接：

HGNC: 13476

OMIM: 605784

KEGG: hsa:57348

UniGene: Hs.268728