TPSB2 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TPSB2 Polyclonal antibody
Uniprot No.：

P20231
基因名：

TPSB2
别名：

Mast cell tryptase beta II antibody; Mast cell tryptase beta III antibody; TPS2 antibody; TPSB2 antibody; TRYB2_HUMAN antibody; Tryptase beta 2 (gene/pseudogene) antibody; Tryptase beta-2 antibody; Tryptase II antibody; Tryptase-2 antibody; TryptaseB antibody; TryptaseC antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Tryptase beta-2 protein (31-275AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.
基因功能参考文献：
1. These observations indicate that betaII-tryptase activity is post-translationally regulated by an allosteric disulfide bond. PMID: 24142694
2. Results indicate a key role for heparin in the activation of human betaI- and beta2-tryptase. PMID: 15567416
3. The disease severity and plasma tryptase levels were not affected by the number of alpha or beta tryptase alleles in mastocytosis patients. PMID: 17449330
4. Strong linkage of TPSAB1 and TPSB2 and pairing of deficiency alleles with functional alleles in observed haplotypes protect human subjects from "knockout" genomes and indeed from inheritance of fewer than 2 active alleles. PMID: 19748655
亚细胞定位：

Secreted. Note=Released from the secretory granules upon mast cell activation.
蛋白家族：

Peptidase S1 family, Tryptase subfamily
数据库链接：

HGNC: 14120

OMIM: 191081

KEGG: hsa:64499

UniGene: Hs.405479