SLC35A2 Antibody

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SLC35A2 Polyclonal antibody
Uniprot No.：

P78381
基因名：

SLC35A2
别名：

SLC35A2 antibody; UGALT antibody; UGT antibody; UGTL antibody; UDP-galactose translocator antibody; Solute carrier family 35 member A2 antibody; UDP-galactose transporter antibody; UDP-Gal-Tr antibody; UGT antibody
宿主：

Rabbit
反应种属：

Human, Mouse,Rat
免疫原：

Synthesized peptide derived from human SLC35A2
免疫原种属：

Homo sapiens (Human)
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen affinity purification
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
产品提供形式：

Liquid
应用范围：

ELISA, WB, IHC
推荐稀释比：

Application Recommended Dilution

WB 1:1000-1:3000

IHC 1:100-1:300
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
基因功能参考文献：
1. The short N-terminal region composed of 35 N-terminal amino-acid residues of UGT was crucial for galactosylation of N-glycans. PMID: 25451267
2. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). PMID: 25944901
3. De novo mutations in SLC35A2 encoding a UDP-galactose transporter cause early-onset epileptic encephalopathy. PMID: 24115232
4. The data further supports the hypothesis that UGT and NGT cooperate in the UDP-Gal delivery for glycosyltransferases located in the Golgi apparatus. PMID: 23583405
5. Mosaicism of the UDP-galactose transporter SLC35A2 causes a congenital disorder of glycosylation. PMID: 23561849
6. localization of the UDP-Gal transporter may depend on the presence of the partner splice variant PMID: 21918738
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相关疾病：

Congenital disorder of glycosylation 2M (CDG2M)
亚细胞定位：

Golgi apparatus membrane; Multi-pass membrane protein.
蛋白家族：

Nucleotide-sugar transporter family, SLC35A subfamily
数据库链接：

HGNC: 11022

OMIM: 300896

KEGG: hsa:7355

STRING: 9606.ENSP00000247138

UniGene: Hs.21899

Application	Recommended Dilution
WB	1:1000-1:3000
IHC	1:100-1:300