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SLC35A2 Antibody, FITC conjugated

  • 中文名称:
    SLC35A2兔多克隆抗体, FITC偶联
  • 货号:
    CSB-PA021584LC01HU
  • 规格:
    ¥880
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) SLC35A2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC35A2
  • 别名:
    SLC35A2 antibody; UGALT antibody; UGT antibody; UGTL antibody; UDP-galactose translocator antibody; Solute carrier family 35 member A2 antibody; UDP-galactose transporter antibody; UDP-Gal-Tr antibody; UGT antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human UDP-galactose translocator protein (136-234AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    FITC
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
  • 基因功能参考文献:
    1. The short N-terminal region composed of 35 N-terminal amino-acid residues of UGT was crucial for galactosylation of N-glycans. PMID: 25451267
    2. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). PMID: 25944901
    3. De novo mutations in SLC35A2 encoding a UDP-galactose transporter cause early-onset epileptic encephalopathy. PMID: 24115232
    4. The data further supports the hypothesis that UGT and NGT cooperate in the UDP-Gal delivery for glycosyltransferases located in the Golgi apparatus. PMID: 23583405
    5. Mosaicism of the UDP-galactose transporter SLC35A2 causes a congenital disorder of glycosylation. PMID: 23561849
    6. localization of the UDP-Gal transporter may depend on the presence of the partner splice variant PMID: 21918738

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  • 相关疾病:
    Congenital disorder of glycosylation 2M (CDG2M)
  • 亚细胞定位:
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Nucleotide-sugar transporter family, SLC35A subfamily
  • 数据库链接:

    HGNC: 11022

    OMIM: 300896

    KEGG: hsa:7355

    STRING: 9606.ENSP00000247138

    UniGene: Hs.21899