PTDSS1 Antibody

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) PTDSS1 Polyclonal antibody
Uniprot No.：

P48651
基因名：

PTDSS1
别名：

PTDSS1 antibody; KIAA0024 antibody; PSSA antibody; Phosphatidylserine synthase 1 antibody; PSS-1 antibody; PtdSer synthase 1 antibody; EC 2.7.8.29 antibody; Serine-exchange enzyme I antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Phosphatidylserine synthase 1 protein (1-35AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，PTDSS1 Antibody (CSB-PA04305A0Rb)，的标记方式是Non-conjugated。对于PTDSS1 Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA04305B0Rb	PTDSS1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA04305C0Rb	PTDSS1 Antibody, FITC conjugated
Biotin	CSB-PA04305D0Rb	PTDSS1 Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA,WB, IHC
推荐稀释比：

Application Recommended Dilution

WB 1:1000-1:3000

IHC 1:100-1:300
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. Catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine.
基因功能参考文献：
1. RYR2, PTDSS1 and AREG are autism susceptibility genes that are implicated in a Lebanese population-based study of copy number variations in this disease. PMID: 26742492
2. PSS1 mutations not only affect cellular PS levels and distribution but also lead to a more complex imbalance in lipid homeostasis by disturbing PI4P metabolism. PMID: 27044099
3. Gain-of-function missense mutations in the phosphatidylserine synthase 1 (PTDSS1) gene cause Lenz-Majewski syndrome. PMID: 24241535
4. Purification and characterization of human phosphatidylserine synthases 1 and 2. PMID: 19014349
相关疾病：

Lenz-Majewski hyperostotic dwarfism (LMHD)
亚细胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

Phosphatidyl serine synthase family
数据库链接：

HGNC: 9587

OMIM: 151050

KEGG: hsa:9791

STRING: 9606.ENSP00000430548

UniGene: Hs.292579

Application	Recommended Dilution
WB	1:1000-1:3000
IHC	1:100-1:300