Il18bp Antibody

中文名称：

Il18bp兔多克隆抗体
货号：

CSB-PA16769A0Rb
规格：

￥440
图片：
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA16769A0Rb at dilution of 1:20
其他：

产品详情

产品名称：

Rabbit anti-Mus musculus (Mouse) Il18bp Polyclonal antibody
Uniprot No.：

Q9Z0M9
基因名：

Il18bp
别名：

Il18bp antibody; Igifbp antibody; Interleukin-18-binding protein antibody; IL-18BP antibody; Interferon gamma-inducing factor-binding protein antibody
宿主：

Rabbit
反应种属：

Mouse
免疫原：

Recombinant Mouse Interleukin-18-binding protein (29-193AA)
免疫原种属：

Mus musculus (Mouse)

标记方式：

Non-conjugated

本页面中的产品，Il18bp Antibody (CSB-PA16769A0Rb)，的标记方式是Non-conjugated。对于Il18bp Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA16769B0Rb	Il18bp Antibody, HRP conjugated	ELISA
FITC	CSB-PA16769C0Rb	Il18bp Antibody, FITC conjugated
Biotin	CSB-PA16769D0Rb	Il18bp Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, IHC
推荐稀释比：

Application Recommended Dilution

IHC 1:10-1:100
Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
基因功能参考文献：
1. IL-18BP ameliorates cardiac ischemia/reperfusion injury in part through suppression of Th17 differentiation. PMID: 26340315
2. Data show that IL-18bp acts as a sensor for IFN-gamma and can regulate both Th1 and Th17 responses in the CNS. PMID: 20644165
3. Administratioan of murine IL-18BP at the time of the booster injection of bovine CII reduces the progressive severity of collagen-induced arthritis; both clinical disease activity and histological scores are decreased by 50%. PMID: 12574381
4. functional polarization of Ag-specific CD4(+) Th2 cells entering the CNS during the accelerating phase of experimental autoimmune encephalomyelitis is flexible and dependent on IL-18, which is overturned by IL-18 binding protein PMID: 15778395
5. IL-18 and IL-18BP may have roles in testicular development, and also in the regulation of testicular functions under physiological conditions PMID: 18299271
6. A single intravenous dose of recombinant mouse IL18BP decreased neointimal hyperplasia and improved arterial L/A ratios in an atherosclerotic balloon-injury animal model. PMID: 18455646
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亚细胞定位：

Secreted.
数据库链接：

KEGG: mmu:16068

STRING: 10090.ENSMUSP00000091685

UniGene: Mm.422756