EGFL6 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) EGFL6 Polyclonal antibody
Uniprot No.：

Q8IUX8
基因名：

EGFL6
别名：

EGF like domain multiple 6 antibody; EGF repeat containing protein 6 antibody; EGF-like protein 6 antibody; EGF-like-domain multiple 6 antibody; egfl6 antibody; EGFL6_HUMAN antibody; epidermal growth factor like protein 6 antibody; Epidermal growth factor-like protein 6 antibody; MAEG antibody; MAM and EGF domain containing antibody; MAM and EGF domains containing gene protein antibody; MAM and EGF domains-containing gene protein antibody; W80 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Epidermal growth factor-like protein 6 protein (301-554AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.
基因功能参考文献：
1. In conclusion, our results suggest that plasma level of EGFL6 may be useful to assess disease progression, and especially advanced T status and higher TNM stage in patients with oral squamous cell carcinoma. PMID: 28539817
2. EGFL6 is an angiocrine and tumor cell factor that promotes tumorigenesis via SHP2-mediated signaling. EGFL6 stimulates ALDH+ ovarian cancer stem cell to migrate and undergo asymmetric division. PMID: 27803106
3. EGFL6 was overexpressed in benign meningioma tissues and serum. PMID: 23285163
4. results indicate that human EGFL6 is a paracrine/autocrine growth factor of adipose tissue up-regulated in obesity and potentially involved in the process of adipose tissue expansion and the development of obesity PMID: 20574786
5. There is an absence of GNAS and EGFL6 mutations in common human cancers. PMID: 18038328
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亚细胞定位：

Secreted, extracellular space, extracellular matrix, basement membrane.
蛋白家族：

Nephronectin family
数据库链接：

HGNC: 3235

OMIM: 300239

KEGG: hsa:25975

STRING: 9606.ENSP00000369976

UniGene: Hs.12844