AOAH Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) AOAH Polyclonal antibody
Uniprot No.：

P28039
基因名：

AOAH
别名：

Acyloxyacyl hydrolase (neutrophil) antibody; Acyloxyacyl hydrolase large subunit antibody; AOAH antibody; AOAH_HUMAN antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Acyloxyacyl hydrolase protein (180-254AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides. By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria.
基因功能参考文献：
1. analysis of AOAH function through its crystal structure and complex with lipopolysaccharide PMID: 29343645
2. AOAH - Gene involved in innate immunity that have been associated with Chronic Rhinosinusitis. PMID: 27888910
3. AOAH rs60023210 variants may be associated with carotid intima-media thickness at bifurcation. PMID: 26319989
4. Polymorphisms in RYBP and AOAH genes are associated with chronic rhinosinusitis in a Chinese population. PMID: 22723975
亚细胞定位：

Secreted. Cytoplasmic vesicle.
数据库链接：

HGNC: 548

OMIM: 102593

KEGG: hsa:313

STRING: 9606.ENSP00000258749

UniGene: Hs.488007