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中文名称：大鼠雌二醇(E2)酶联免疫试剂盒
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货号：CSB-E05110r
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规格：96T/48T
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价格：￥3900/￥2500
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其他：
产品详情
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产品描述：CUSABIO大鼠雌二醇（E2）酶联免疫检测试剂盒（货号：CSB-E05110r），采用竞争法原理定量分析血清、血浆样本中的E2水平。雌二醇（E2）作为重要的类固醇激素，在生殖系统发育、骨代谢调控及心血管功能维持中发挥关键作用，广泛应用于生殖生理、内分泌疾病模型构建及药物代谢等科研领域。试剂盒检测浓度范围为50-1200 pg/ml，通过预包被抗体与样本中的E2及酶标物进行特异性竞争结合，结合显色强度与目标物浓度呈负相关，实现精准定量分析。该试剂盒适用于大鼠模型研究中卵巢功能评估、妊娠状态监测、环境激素暴露分析以及激素替代疗法的效果验证，为内分泌相关机制探索提供可靠数据支持。实验操作全程约需3.5小时，配套提供标准品、检测抗体及显色底物，96孔板规格适配常规实验室检测需求，建议用户通过标准曲线绘制进行样本浓度计算。
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别名：N/A
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缩写：E2
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种属：Rattus norvegicus (Rat)
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样本类型：serum, plasma
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检测范围：50 pg/ml-1200 pg/ml.
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灵敏度：40 pg/ml.
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Signal Transduction
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测定原理：quantitative
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测定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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标准曲线：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
pg/ml
OD1
OD2
Average
0
2.417
2.534
2.476
50
1.287
1.367
1.327
120
0.848
0.828
0.838
250
0.582
0.579
0.581
500
0.384
0.361
0.373
1200
0.248
0.253
0.251
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数据处理：
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货期：3-5 working days
引用文献
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- Huyang Yangkun formula regulates the mitochondria pathway of ovarian granulosa cell apoptosis through FTO/ m6A-P53 pathway Y Li, L Wang, J Liu, G Nie, H Yang,Frontiers in Pharmacology,2024
- The therapeutic effects of curcumin on polycystic ovary syndrome by upregulating PPAR-γ expression and reducing oxidative stress in a rat model W Zhang, C Peng, L Xu, Y Zhao, C Huang,Frontiers in Endocrinology,2024
- MSCs–derived EVs protect against chemotherapy-induced ovarian toxicity: role of PI3K/AKT/mTOR axis NM Elsherbiny, MS Abdel-Maksoud, K Prabahar,Journal of Ovarian Research,2024
- Impacto de la manipulación hormonal y epigenética sobre la falta de efecto del receptor GABAᴀ α₆ espinal en ratas macho con dolor neuropático P Encarnación, J Miguel,Thesis&Dissertation,2024
- The ameliorative effects of bee bread supplement on the ovarian dysfunction induced by high-fat diet: Comparison with S. officinalis and shifting to normal diet supplement GM Ezzat, MF Ali, HAA Hussein,Journal of Advanced Veterinary Research,2024
- Ameliorative Effect of Chitosan/Spirulina platensis Ethanolic Extract Nanoformulation against Cyclophosphamide-Induced Ovarian Toxicity: Role of PPAR-γ/Nrf-2/HO-1 and NF-kB/TNF-α Signaling Pathways M Almukainzi, TA El-Masry, HA Ibrahim, HM Saad,Marine Drugs,2024
- The crucial role of beta-catenin in the osteoprotective effect of semaglutide in an ovariectomized rat model of osteoporosis MHH Abo-Elenin, R Kamel, S Nofal,Naunyn-Schmiedeberg's Archives of Pharmacology,2024
- Bone marrow mesenchymal stem cells expressing Neat-1, Hotair-1, miR-21, miR-644, and miR-144 subsided cyclophosphamide-induced ovarian insufficiency by remodeling the IGF-1–kisspeptin system, ovarian apoptosis, and angiogenesis AI Ahmed, MF Dowidar, AF Negm, H Abdellatif,Journal of Ovarian Research,2024
- The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg F Zhu,European journal of nutrition,2024
- Ketamine causes poor maternal care in rats with postpartum depression and leads to few behavioral and neurochemical alterations on male offspring J Zaccarelli-Magalhães,Behavioural brain research,2023
- Age-related changes in densitometry and histomorphometry of long bone during the pubertal growth spurt in male rats K Ryu,Anatomical science international,2024
- Zhibai Dihuang pill (ZBDH) exhibits therapeutic effects on idiopathic central sexual precocity in rats by modulating the Gut Microflora C Yi,Heliyon,2024
- Combined supplementation with hesperidin, phytosterols and curcumin decreases adiposity and improves metabolic health in ovariectomized rats J Baudin,Food & function,2024
- The Herbal Combination Shu Gan Jie Yu Regulates the SNCG/ER-a/AKT-ERK Pathway in DMBA-Induced Breast Cancer and Breast Cancer Cell Lines Based on RNA-Seq and IPA Analysis Y Zhao,Integrative cancer therapies,2024
- Tortoise-shell glue ameliorates male infertility through the hypothalamic-pituitary-gonadal axis in obese rats W Sheng,/,2024
- The role of the indoleamine 2, 3-dioxygenase gene in preventing ovarian transplant rejection in rats A Long,Biology of reproduction,2024
- Syzygium malaccense leaves methanol extract modulate some biochemical and inflammatory markers and prostate histology of testosterone-estradiol valerate induced benign prostatic hyperplasia in rats NK Achi,/,2023
- Chronic Fluoride Exposure Induces Ovarian Dysfunction and Potential Association with Premature Ovarian Failure in Female Rats X Tang,Biological trace element research,2023
- Cuphea Ignea Extract Relieved the Histological Changes and Activated the NF-ҠB Protein of Female Reproductive Organs and Stomach in EtOH-Treated Rats AENA Madbolia,Egyptian Journal of Chemistry,2023
- Comprehensive metabolite profiling of Phoenix rupicola pulp and seeds using UPLC-ESI-MS/MS and evaluation of their estrogenic activity in ovariectomized rat model EM AbouZeid,Food Research International,2023
- Constant light exposure alters gut microbiota and short‐/medium‐chain fatty acids and aggravates PCOS‐like traits in HFD‐fed rats F Yue,Obesity,2023
- The anti-androgenic effect of quercetin on hyperandrogenism and ovarian dysfunction induced in a dehydroepiandrosterone rat model of polycystic ovary syndrome AA Mahmoud,Steroids,2023
- Altered m6A modification is involved YAP-mediated apoptosis response in 4-vinylcyclohexene diepoxide induced ovotoxicity Y Li,Ecotoxicology and environmental safety,2023
- Rapamycin Induced Autophagy in Mesenchymal Stem Cells Modulates Cell Survival After Transplantation in a Rat Model with Cisplatin-Induced Ovarian Toxicity via Deactivation of the mTOR Pathway A Sarhan,preprints,2023
- Melatonin Mitigates Cisplatin-Induced Ovarian Dysfunction via Altering Steroidogenesis, Inflammation, Apoptosis, Oxidative Stress, and PTEN/PI3K/Akt/mTOR/AMPK Signaling Pathway in Female Rats A Al-Shahat,Pharmaceutics,2022
- Potential Protective Effect of Bromelain and Pineapple Extract on Gamma Irradiated Female Rats: A Study of Oxidative Stress, Apoptosis, and Hormonal Changes D Fouad,Journal of Food and Nutrition Research,2022
- Quercetin Abates Aluminum Trioxide Nanoparticles and Lead Acetate Induced Altered Sperm Quality, Testicular Oxidative Damage, and Sexual Hormones Disruption in Male Rats A Behairy,Antioxidants,2022
- Mechanistic insights into the protective role of eugenol against stress-induced reproductive dysfunction in female rat model H Helmy,Chemico-biological interactions,2022
- Mentha pulegium L. (Pennyroyal, Lamiaceae) Extracts Impose Abortion or Fetal-Mediated Toxicity in Pregnant Rats; Evidenced by the Modulation of Pregnancy Hormones, MiR-520, MiR-146a, TIMP-1 and MMP-9 Protein Expressions, Inflammatory State, Certain Relate AA El-Gazar,Toxins,2022
- Panax Ginseng alleviates thioacetamide-induced liver injury in ovariectomized rats: Crosstalk between inflammation and oxidative stress RE Mostafa,PLoS One,2021
- Ameliorative Effects of Pueraria lobata Extract on Postmenopausal Symptoms through Promoting Estrogenic Activity and Bone Markers in Ovariectomized Rats MR Lee,Evidence-Based Complementary and Alternative Medicine,2021
- Comorbidity: Chronic neurogenic pain affects malignant growth and changes balance of neurosteroids in brain of rats Yulia A,Journal of Clinical Oncology,2021
- Differing effects of estrogen deficiency on the contractile function of atrial and ventricular myocardium A Khokhlova,Biochemical and Biophysical Research Communications,2021
- Effect of Light-Dark Cycle Misalignment on the Hypothalamic-Pituitary-Gonadal Axis, Testicular Oxidative Stress, and Expression of Clock Genes in Adult Male Rats A Moustafa,International journal of endocrinology,2020
- Estrogen re-enhanced prenatal stress-related visceral sensitization and pain regulation J Chen,Research Square,2020
- Lactobacillus‐fermented milk products attenuate bone loss in an experimental rat model of ovariectomy‐induced post‐menopausal primary osteoporosis CS Lee,Journal of applied microbiology,2020
- The effects of metformin treatment on the ovaries and uterus of offspring S Kırmızıkan,Journal Gynecological Endocrinology,2020
- Beneficial phytoestrogenic effects of resveratrol on polycystic ovary syndromein rat model N Zhang,Journal Gynecological Endocrinology,2020
- CUMS Promotes the Development of Premature Ovarian Insufficiency Mediated by Nerve Growth Factor and Its Receptor in Rats X Fu,BioMed Research International,2020
- Prognosis Evaluation Using 18F-Alfatide II PET in a Rat Model of Spinal Cord Injury Treated With Estrogen H Tan,Mol Imaging,2020
- The phytoestrogen, quercetin, in serum, uterus and ovary as a potential treatment for dehydroepiandrosterone-induced polycystic ovary syndrome in the rat Khorchani M J, et al,Reproduction, Fertility and Development,2019
- Doxorubicin-induced toxicity to 3D-cultured rat ovarian follicles on a microfluidic chip Yu X, et al,Toxicology In Vitro,2019
- Vitamin D3 Modulates NF-kB/p65, 17β-Estradiol, and Vitamin D Receptors Expression at Estrogen Deficiency Koshkina A, et al,Vitamin D Defjciency,2019
- Mercury affects uterine myogenic activity even without producing any apparent toxicity in rats: Involvement of calcium-signaling cascades Swati Koli, et al,Journal of Trace Elements In Medicine and Biology,2019
- Abnormal expression of HSP70 may contribute to PCOS pathology Wu G, et al,Journal of Ovarian Research,2019
- Dietary Supplements of Barley and Date-Palm Fruit Improved the Growth Defects of Ovaries of Rat Offspring Maternally Fed on Hypercholesterolemic Diet Hassan I. H. El-Sayyad, et al,Biosci Biotech Res Asia,2019
- Inhibition of MSTN signal pathway may participate in LIPUS preventing bone loss in ovariectomized rats Liang Tang, et al,Journal of Bone and Mineral Metabolism,2019
- Umbilical Cord Mesenchymal Stem Cell Transplantation Prevents Chemotherapy-Induced Ovarian Failure via the NGF/TrkA Pathway in Rats Qun Zheng,BioMed Research International,2019
- Effects of VEGF + Mesenchymal Stem Cells and Platelet-Rich Plasma on Inbred Rat Ovarian Functions in Cyclophosphamide-Induced Premature Ovarian Insufficiency Model Vural B,Stem Cell Reviews and Reports,2019
- Effects of VEGF + Mesenchymal Stem Cells and Platelet-Rich Plasma on Inbred Rat Ovarian Functions in Cyclophosphamide-Induced Premature Ovarian Insufficiency Model Vural B,Stem Cell Reviews and Reports,2019
- Zuogui Pills inhibit mitochondria-dependent apoptosis of follicles in a rat model of premature ovarian failure Peng H, et al,Journal of Ethnopharmacology,2019
- The Effect of Electromagnetic Fields of Extremely Low Frequency 30 Hz on Rat Ovaries Alekperov SI, et al,Bulletin of Experimental Biology and Medicine,2019
- Impact of Hydroalcoholic Extract of Humulus Lupulus L. on Sperm Quality, Reproductive Organs and Hormones in Male Rat Karbalaei N, et al,Chinese journal of integrative medicine,2019
- EFFECTS of GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM 17-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATS Syami Yulianti, et al,/,2018
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- Quercetin interferes with the fluid volume and receptivity development of the uterus in rats during the peri-implantation period Huma Shahzad.et al,Reprod Toxicol.,2017
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- Peri-pubertal high caffeine exposure increases ovarian estradiol production in immature rats Yoojin Kwak.et al,Reproductive Toxicology,2017
- A cell-based model of bone remodeling for identifying activity of icarrin in the treatment of osteoporosis. Liu YQ.et al,Biotechnol Lett.,2015
- Peripubertal Caffeine Exposure Impairs Longitudinal Bone Growth in Immature Male Rats in a Dose- and Time-Dependent Manner Choi YY.et al,J Med Food.,2016
- Mammary gland epithelial changes in thyroidectomized female rats Vasilios Pergialiotis et al,JBUON,2015
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- Ameliorative potential of stem bromelain on lead-induced toxicity in Wistar rats Al-Otaibi WR. et al,Acta Biol Hung,2015
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最新研究进展：Estradiol (E2)是一种雌激素，是雌二醇的最常见形式之一。它在雌性哺乳动物中发挥着重要的生理作用，如促进生殖器官的发育和维护，调节月经周期，维护骨密度等。最近的研究表明，E2在心血管健康、代谢疾病、神经退行性疾病和癌症等多个方面也起着重要的作用。
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