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中文名称:大鼠组织蛋白酶B(CTSB)酶联免疫试剂盒
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货号:CSB-EL006185RA
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规格:96T/48T
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价格:¥3600/¥2500
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其他:
产品详情
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产品描述:CUSABIO大鼠组织蛋白酶B(CTSB)酶联免疫试剂盒(货号:CSB-EL006185RA),采用双抗体夹心法定量检测血清、血浆、组织匀浆及细胞裂解液中的CTSB含量。组织蛋白酶B是一种溶酶体半胱氨酸蛋白酶,广泛参与蛋白质降解、细胞凋亡及炎症调控等过程,其表达水平与神经退行性疾病、肿瘤微环境等病理机制研究密切相关。试剂盒检测范围为18.75 ng/mL至1200 ng/mL,通过预包被特异性抗体捕获样本中的CTSB,结合酶标二抗显色反应实现精准定量。该试剂盒适用于体外实验研究,可支持基础科研中CTSB在细胞模型、动物疾病模型或药物干预实验中的动态监测,例如溶酶体功能分析、组织损伤修复机制探索或相关信号通路研究,为深入解析CTSB的生物学功能及病理学意义提供可靠工具。所有操作均需严格按照说明书进行,确保实验重复性与数据准确性。
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别名:Ctsb ELISA Kit; Cathepsin B ELISA Kit; EC 3.4.22.1 ELISA Kit; Cathepsin B1 ELISA Kit; RSG-2) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain] ELISA Kit
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缩写:
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Uniprot No.:
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种属:Rattus norvegicus (Rat)
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样本类型:serum, plasma, tissue homogenates, cell lysates
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检测范围:18.75 ng/mL-1200 ng/mL
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灵敏度:4.67 ng/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Signal Transduction
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测定原理:quantitative
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测定方法:Sandwich
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数据处理:
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货期:3-5 working days
引用文献
- Graphene oxide induces p62/SQSTM-dependent apoptosis through the impairment of autophagic flux and lysosomal dysfunction in PC12 cells Feng X.et al,Acta Biomaterialia,2018
相关产品
靶点详情
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功能:Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.
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亚细胞定位:Lysosome. Melanosome. Secreted, extracellular space. Apical cell membrane; Peripheral membrane protein; Extracellular side.
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蛋白家族:Peptidase C1 family
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组织特异性:Expressed in the epithelial cells of the prostate and mammary gland.
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数据库链接:
STRING: 10116.ENSRNOP00000014178
UniGene: Rn.100909
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