Mouse thrombospondin 1,TSP-1 ELISA Kit
产品详情
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产品描述:
CUSABIO小鼠血小板反应蛋白/凝血酶敏感蛋白1(TSP-1)酶联免疫检测试剂盒(货号:CSB-E08765m),采用双抗体夹心法定量检测血清、血浆或组织匀浆样本中的TSP-1浓度。TSP-1是一种参与细胞间相互作用、血管生成及组织修复调控的多功能糖蛋白,其表达水平与炎症反应、肿瘤微环境及心血管疾病等研究领域密切相关。该试剂盒检测范围为3.12 ng/ml至200 ng/ml,灵敏度达3.12 ng/ml,可精准覆盖生理及实验条件下的小鼠TSP-1浓度变化范围。试剂盒包含预包被特异性捕获抗体、生物素标记检测抗体、标准品及TMB显色系统,操作流程兼容常规ELISA平台,适用于体外研究中小鼠模型的血浆、血清样本分析,或特定组织(如肝脏、血管等)匀浆中TSP-1的表达水平检测。其高特异性和稳定性使其成为探究TSP-1在血管生成调控、纤维化进程或肿瘤免疫微环境等科研方向中的可靠工具,为分子机制研究及药物开发提供数据支持。
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别名:
Thbs1 ELISA Kit; Tsp1 ELISA Kit; Thrombospondin-1 ELISA Kit; Glycoprotein G ELISA Kit
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缩写:
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Uniprot No.:
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种属:
Mus musculus (Mouse)
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样本类型:
serum, plasma, tissue homogenates
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检测范围:
3.12 ng/ml-200 ng/ml
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灵敏度:
1.56 ng/ml
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反应时间:
1-5h
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样本体积:
50-100ul
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检测波长:
450 nm
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研究领域:
Cardiovascular
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测定原理:
quantitative
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测定方法:
Sandwich
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本试剂盒不含材料:
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数据处理:
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货期:
3-5 working days
引用文献
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Approaching Thrombospondin-1 as a Potential Target for Mesenchymal Stromal Cells to Support Liver Regeneration after Partial Hepatectomy in Mouse and Humans
L Tietze,Cells,2024
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The Effect of Metformin in EML4-ALK+ Lung Cancer alone and in Combination with Crizotinib in Cell and Rodent Models
AR Bland,Biochemical Pharmacology,2020
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Mouse skin-derived precursors alleviates ultraviolet B irradiation damage via early activation of TGF-β/Smad pathway by thrombospondin1
Y Li,Cell Cycle,2020
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Endothelial MT1-MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis
Esteban S, et al,Embo Molecular Medicine,2019
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Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin
Fossati G, et al,Embo Journal,2018
靶点详情
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最新研究进展:
THBS1是一种血小板聚集素,最近的研究表明它在肿瘤生长和转移中发挥着重要作用。研究表明,THBS1可以促进血管生成和癌细胞的增殖,并与癌细胞的生长和转移有关。此外,THBS1还参与了许多其他疾病的发生和发展,包括动脉粥样硬化、肝病和神经退行性疾病等。
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功能:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp. Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors.
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亚细胞定位:
Secreted. Cell surface. Secreted, extracellular space, extracellular matrix. Endoplasmic reticulum. Sarcoplasmic reticulum.
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蛋白家族:
Thrombospondin family
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数据库链接:
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