-
中文名称：人可溶性肿瘤坏死因子样凋亡微弱诱导剂(sTWEAK)酶联免疫试剂盒
-
货号：CSB-E16492h
-
规格：96T/48T
-
价格：￥3600/￥2500
-
其他：
产品详情
-
产品描述：人可溶性肿瘤坏死因子样凋亡微弱诱导剂(sTWEAK)酶联免疫试剂盒（CSB-E16492h）为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的TNFSF12含量。TNFSF12，又称TWEAK，是一种肿瘤坏死因子超家族成员，具有诱导细胞凋亡、促进血管生成和参与炎症反应等功能。其通过与FN14受体结合，在肿瘤发生发展中发挥重要作用，并与多种疾病如肝癌、胆道闭锁等密切相关。试剂盒检测范围为0.312 ng/ml-20 ng/ml，灵敏度为0.078 ng/ml。可用于细胞因子网络研究、疾病动物模型验证及生物标志物筛查等方向，支持体外实验样本中 sTWEAK 蛋白的精准定量分析。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
-
别名：APO 3 ligand ELISA Kit; APO 3L ELISA Kit; APO3 ligand ELISA Kit; APO3/DR3 ligand ELISA Kit; APO3L ELISA Kit; DR3LG ELISA Kit; MGC129581 ELISA Kit; MGC20669 ELISA Kit; secreted form ELISA Kit; TNF-related weak inducer of apoptosis ELISA Kit; TNF12_HUMAN ELISA Kit; TNFSF 12 ELISA Kit; Tnfsf12 ELISA Kit; TNFSF12 protein ELISA Kit; Tumor necrosis factor (ligand) superfamily member 12 ELISA Kit; Tumor necrosis factor ligand superfamily member 12 ELISA Kit; Tumor necrosis factor superfamily member 12 ELISA Kit; TWEAK ELISA Kit; UNQ181/PRO207 ELISA Kit
-
缩写：
-
Uniprot No.：
-
种属：Homo sapiens (Human)
-
样本类型：serum, plasma, tissue homogenates
-
检测范围：0.312 ng/ml-20 ng/ml
-
灵敏度：0.078 ng/ml
-
反应时间：1-5h
-
样本体积：50-100ul
-
检测波长：450 nm
-
研究领域：Cardiovascular
-
测定原理：quantitative
-
测定方法：Sandwich
-
精密度：
-
线性度：
-
回收率：
-
标准曲线：
-
数据处理：
-
货期：3-5 working days
引用文献
- Increased Serum Concentrations of TNF-Like Weak Inducer of Apoptosis Predict Higher 28-Day Mortality in Patients with Sepsis Ying Guo, et al,Emergency Medicine International,2019
- Increased serum tumor necrosis factor receptor-associated factor-6 expression in patients with non-metastatic triple-negative breast cancer Cemil Bilir et al,Oncology Letters,2015
产品评价
相关产品
靶点详情
-
最新研究进展：TNFSF12是一种细胞因子，也被称为TWEAK。最新的研究表明，它在肝癌等多种肿瘤的发生和进展中发挥着关键作用，并且可能成为治疗这些肿瘤的新靶点之一。
-
功能：Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
-
基因功能参考文献：
- Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
- Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
-
亚细胞定位：Cell membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted.; [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein.
-
蛋白家族：Tumor necrosis factor family
-
组织特异性：Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Als
-
数据库链接：
Most popular with customers
-
Human Transforming Growth factor β1,TGF-β1 ELISA kit
Detect Range: 23.5 pg/ml-1500 pg/ml
Sensitivity: 5.8 pg/ml
-
-
-
Mouse Tumor necrosis factor α,TNF-α ELISA Kit
Detect Range: 7.8 pg/ml-500 pg/ml
Sensitivity: 1.95 pg/ml
-
-
-
-
