XIAP
XIAP，即X染色体连锁的凋亡抑制蛋白，别名HILP、IAP 3。它是一种由XIAP基因编码的蛋白质，属于凋亡抑制蛋白家族成员，在多种细胞类型中表达。XIAP的作用机制主要通过直接抑制凋亡蛋白酶，如caspase-3、-7、-9，从而阻断细胞凋亡的效应阶段。XIAP还能通过与Smurf1、Tolloid等蛋白相互作用，参与细胞周期调控和发育过程。XIAP的意义非常广泛，它参与了细胞存活、免疫调节、细胞凋亡等多种生理和病理过程。XIAP的异常表达与某些癌症的发生发展密切相关，使其成为抗肿瘤药物开发的潜在靶点。
热销产品
Recombinant Human E3 ubiquitin-protein ligase XIAP (XIAP) (CSB-EP026193HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
XIAP Antibody (CSB-PA026193LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA026193LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA026193LA01HU at dilution of 1:100
XIAP Antibodies
XIAP for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA026193GA01HU | XIAP Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA026193ESR2HU | XIAP Antibody | Human | ELISA, WB, IHC |
| CSB-PA026193LA01HU | XIAP Antibody | Human | ELISA, IHC |
| CSB-PA026193LB01HU | XIAP Antibody, HRP conjugated | Human | ELISA |
| CSB-PA026193LC01HU | XIAP Antibody, FITC conjugated | Human | |
| CSB-PA548634 | Phospho-XIAP (Ser87) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004519 | XIAP Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA009303 | Phospho-XIAP (S87) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA968176 | XIAP Antibody | Human,Mouse,Rat | ELISA,WB |
XIAP Proteins
XIAP Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP026193HU CSB-BP026193HU CSB-MP026193HU CSB-EP026193HU-B |
Recombinant Human E3 ubiquitin-protein ligase XIAP (XIAP) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP026193HU | Recombinant Human E3 ubiquitin-protein ligase XIAP (XIAP) | E.coli |
| CSB-EP026193HU(M) | Recombinant Human E3 ubiquitin-protein ligase XIAP (XIAP) (1-1:M→MM) | E.coli |
| CSB-EP026193HU(M1) | Recombinant Human E3 ubiquitin-protein ligase XIAP (XIAP)(E134D) | E.coli |
XIAP Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP026193XBE CSB-EP026193XBE CSB-BP026193XBE CSB-MP026193XBE CSB-EP026193XBE-B |
Recombinant Xenopus laevis Baculoviral IAP repeat-containing protein 4 (xiap) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
XIAP Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP710677XBF CSB-EP710677XBF CSB-BP710677XBF CSB-MP710677XBF CSB-EP710677XBF-B |
Recombinant Xenopus tropicalis E3 ubiquitin-protein ligase XIAP (xiap) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
XIAP Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP726691MO CSB-EP726691MO CSB-BP726691MO CSB-MP726691MO CSB-EP726691MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase XIAP (Xiap) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
XIAP Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP865627RA CSB-EP865627RA CSB-BP865627RA CSB-MP865627RA CSB-EP865627RA-B |
Recombinant Rat E3 ubiquitin-protein ligase XIAP (Xiap) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
