TRIM72
TRIM72,全称为Tripartite Motif Containing 72,是一种肌肉特异性蛋白,也被称为Mitsugumin-53或Mg53。它在细胞膜修复中扮演重要角色,能够修复受损的细胞膜,并参与细胞自噬过程。TRIM72与多种信号通路有关,如胰岛素受体信号通路和肌管分化的负调控。此外,TRIM72的异常与某些疾病相关,如肌萎缩侧索硬化(渐冻症)。近年来,针对TRIM72的药物研发取得进展,例如全球首款针对渐冻症的基因治疗药物SNUG01,它通过递送工程化TRIM72基因来修复受损的神经元,为渐冻症患者带来了新的治疗希望。
热销产品
Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial (CSB-EP744394HU)
验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TRIM72 Antibody (CSB-PA080146)
验证数据

Immunohistochemical analysis of paraffin-embedded Mouse PancreasTissue using TRIM72 Polyclonal Antibody.

Western blot analysis of Mouse skeletal muscle using TRIM72 Polyclonal Antibody.
Human Tripartite motif-containing protein 72(TRIM72) ELISA kit (CSB-EL024511HU)
验证数据

货号:CSB-EL024511HU
规格:96T/48T
灵敏度:6.25 pg/mL
检测范围:25 pg/mL-1600 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
TRIM72 Antibodies
TRIM72 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA080146 | TRIM72 Antibody | Human,Mouse,Rat | WB, IHC |
TRIM72 Proteins
TRIM72 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP744394HU CSB-EP744394HU-B |
Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | Yeast In Vivo Biotinylation in E.coli |
CSB-MP744394HU | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | Mammalian cell |
CSB-EP744394HU1(M) | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | E.coli |
CSB-EP744394HU1 | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | E.coli |
CSB-BP744394HU | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | Baculovirus |
CSB-EP744394HU | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | E.coli |
TRIM72 ELISA Kit
TRIM72 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL024511HU | Human Tripartite motif-containing protein 72(TRIM72) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 6.25 pg/mL |