TRAM1
TRAM1，即易位相关膜蛋白1，别名TRAM、PNAS8、TRAMP。这是一种在人类细胞内质网中表达的多通道膜蛋白。TRAM1的作用机制涉及影响糖基化，并在新生多肽链的易位暂停期间，通过调节哪些结构域对胞质溶胶可见，来促进分泌蛋白跨内质网膜的易位。它还可能影响SEC61通道附近的磷脂双层，从而促进蛋白质的内质网运输，并在内质网应激条件下，参与未折叠蛋白反应（UPR）中的蛋白质降解过程。TRAM1在多种生物学过程中发挥作用，包括宿主-病毒相互作用、蛋白质运输、易位和未折叠蛋白反应。异常的TRAM1表达与多种疾病相关，如Meckel综合征2型、Oropouche热、神经细胞脂褐质沉积症8型Northern癫痫变体、Varadi-Papp综合征等。
热销产品
Recombinant Human Translocating chain-associated membrane protein 1 (TRAM1), partial
CSB-YP618990HU
来源：Yeast
CSB-EP618990HU
来源：E.coli
CSB-BP618990HU
来源：Baculovirus
CSB-MP618990HU
来源：Mammalian cell
CSB-EP618990HU-B
来源：In Vivo Biotinylation in E.coli
TRAM1 Antibodies
TRAM1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA024221GA01HU | TRAM1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
TRAM1 Proteins
TRAM1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP618990HU CSB-EP618990HU CSB-BP618990HU CSB-MP618990HU CSB-EP618990HU-B |
Recombinant Human Translocating chain-associated membrane protein 1 (TRAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Pongo abelii (Sumatran orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP719168PYX CSB-EP719168PYX CSB-BP719168PYX CSB-MP719168PYX CSB-EP719168PYX-B |
Recombinant Pongo abelii Translocating chain-associated membrane protein 1 (TRAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP723043RA CSB-EP723043RA CSB-BP723043RA CSB-MP723043RA CSB-EP723043RA-B |
Recombinant Rat Translocating chain-associated membrane protein 1 (Tram1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP852767MO CSB-EP852767MO CSB-BP852767MO CSB-MP852767MO CSB-EP852767MO-B |
Recombinant Mouse Translocating chain-associated membrane protein 1 (Tram1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRAM1 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP875599BO CSB-EP875599BO CSB-BP875599BO CSB-MP875599BO CSB-EP875599BO-B |
Recombinant Bovine Translocating chain-associated membrane protein 1 (TRAM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
