TNFSF4
TNFSF4，即肿瘤坏死因子超家族成员4，别名TXGP1;Glycoprotein Gp34、OX40 ligand、OX40L、TAX transcriptionally-activated glycoprotein 1、CD antigen CD252。它是一种主要由活化的T细胞产生的细胞膜结合蛋白，属于肿瘤坏死因子超家族成员之一，由人体细胞自身的基因编码。TNFSF4的作用机制主要是通过与其受体OX40（TNFRSF4，CD134）结合，这一结合在T细胞的激活、增殖和存活中发挥关键作用。TNFSF4-OX40的相互作用可以促进T细胞的二次信号，增强T细胞的效应功能，同时在调节免疫应答和促进免疫记忆形成中起到重要作用。TNFSF4-OX40信号通路在CD4+和CD8+ T细胞的扩增、分化和存活中起着至关重要的作用，特别是在T细胞依赖的免疫应答中。此外，TNFSF4也在调节自身免疫反应和炎症过程中发挥作用，其异常表达或功能失调与某些自身免疫性疾病的发生发展有关。因此，TNFSF4是免疫学研究和相关疾病治疗中的一个潜在靶点，针对TNFSF4的治疗策略正在被开发用于治疗某些类型的癌症和自身免疫性疾病。
热销产品
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TNFSF4 Antibody (CSB-PA006280)
验证数据
Western Blot analysis of KB cells using Ox40L Polyclonal Antibody
Western Blot analysis of KB cells using Ox40L Polyclonal Antibody
Human soluble OX40L (sOX40L) ELISA kit (CSB-E12752h)
验证数据
货号：CSB-E12752h
规格：96T/48T
灵敏度：0.039 ng/mL
检测范围：0.156 ng/mL-10 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
TNFSF4 Antibodies
TNFSF4 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA006280 | TNFSF4 Antibody | Human | WB, ELISA |
| CSB-PA060031 | TNFSF4 Antibody | Human | IF, ELISA |
| CSB-PA920694 | TNFSF4 Antibody | Human | ELISA,IHC |
TNFSF4 Proteins
TNFSF4 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP023994HU1 CSB-EP023994HU1 CSB-BP023994HU1 CSB-EP023994HU1-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF023994HU | Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4) | in vitro E.coli expression system |
| CSB-AP005261HU | Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial (Active) | Mammalian cell |
| CSB-MP023994HU1 | Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial | Mammalian cell |
| CSB-MP023994HU1c9 | Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial | Mammalian cell |
| CSB-MP023994HU1-B | Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial, Biotinylated | Mammalian cell |
TNFSF4 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP023994MO1 CSB-EP023994MO1 CSB-BP023994MO1 CSB-MP023994MO1 CSB-EP023994MO1-B |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 4 (Tnfsf4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF023994MO | Recombinant Mouse Tumor necrosis factor ligand superfamily member 4 (Tnfsf4) | in vitro E.coli expression system |
TNFSF4 Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP023994RB1-B |
Recombinant Rabbit Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial | In Vivo Biotinylation in E.coli |
| CSB-CF023994RB | Recombinant Rabbit Tumor necrosis factor ligand superfamily member 4 (TNFSF4) | in vitro E.coli expression system |
| CSB-BP023994RB1 | Recombinant Rabbit Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial | Baculovirus |
| CSB-MP023994RB1 | Recombinant Rabbit Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial | Mammalian cell |
| CSB-EP023994RB1 | Recombinant Rabbit Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial | E.coli |
| CSB-YP023994RB1 | Recombinant Rabbit Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial | Yeast |
TNFSF4 ELISA Kit
TNFSF4 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E12752h | Human soluble OX40L (sOX40L) ELISA kit | serum, plasma, tissue homogenates | 0.039 ng/mL |
TNFSF4 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL023994MO | Mouse Tumor necrosis factor ligand superfamily member 4(TNFSF4) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 3.9 pg/mL |
