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TNFSF11

TNFSF11,即肿瘤坏死因子超家族成员11,别名OPGL、RANKL、TRANCE,是一种关键的细胞因子,在骨代谢、免疫系统和肿瘤生物学中扮演重要角色。由T细胞产生,TNFSF11通过与其受体RANK结合,激活NF-κB信号通路,促进破骨细胞的分化和活性,影响骨吸收。异常的TNFSF11表达与骨质疏松症、骨转移癌等疾病有关,同时在肿瘤微环境中可能促进肿瘤细胞的侵袭和转移,使其成为治疗相关疾病的潜在靶点。

热销产品

Recombinant Human Tumor necrosis factor ligand superfamily member 11 (TNFSF11), partial (CSB-MP023986HU(F2))

验证数据

CSB-MP023986HU(F2)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TNFSF11 Antibody (CSB-PA023986LA01HU)

验证数据

CSB-PA023986LA01HU

Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA023986LA01HU at dilution of 1:100

CSB-PA023986LA01HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023986LA01HU at dilution of 1:100

CSB-PA023986LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA023986LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

TNFSF11 Antibodies

TNFSF11 for Mus musculus (Mouse)

TNFSF11 for Homo sapiens (Human)

TNFSF11 Proteins

TNFSF11 Proteins for Mus musculus (Mouse)

TNFSF11 Proteins for Homo sapiens (Human)

TNFSF11 Proteins for Rattus norvegicus (Rat)

TNFSF11 ELISA Kit

TNFSF11 ELISA Kit for Homo sapiens (Human)

TNFSF11 ELISA Kit for Mus musculus (Mouse)

TNFSF11 ELISA Kit for Rattus norvegicus (Rat)