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TNC

TNC,即神经胶质素C,别名Tenascin-C、TN,是一种广泛分布于细胞外基质中的大型糖蛋白,主要由成纤维细胞、内皮细胞和平滑肌细胞等分泌。TNC具有独特的多域结构,能够与多种细胞表面受体(如整合素、Notch受体)及其它细胞外基质成分相互作用,通过调节细胞粘附、迁移、增殖和分化等过程,参与组织的发育、重塑及修复。在生理状态下,TNC对于维持组织稳态和促进伤口愈合具有重要作用。然而,在病理条件下,如肿瘤发生发展过程中,TNC的异常高表达可促进癌细胞的侵袭和转移,参与构建有利于肿瘤生长的微环境,成为疾病进展的关键因素之一。此外,TNC还与慢性炎症、纤维化等疾病相关,显示出其在多种生物学过程中的复杂角色。

热销产品

Recombinant Human Tenascin (TNC), partial (CSB-RP115094h(C))

验证数据

CSB-RP115094h(C)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-RP115094h(C)

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP115094h(C) could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TNC.

CSB-RP115094h(C)

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP115094h(C) could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TNC.

TNC Antibody (CSB-PA11509A0Rb)

验证数据

CSB-PA11509A0Rb

Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA11509A0Rb at dilution of 1:50

TNC Antibodies

TNC for Homo sapiens (Human)

TNC Proteins

TNC Proteins for Gallus gallus (Chicken)

TNC Proteins for Homo sapiens (Human)

TNC Proteins for Sus scrofa (Pig)

TNC Proteins for Mus musculus (Mouse)

TNC ELISA Kit

TNC ELISA Kit for Mus musculus (Mouse)

TNC ELISA Kit for Homo sapiens (Human)