TBC1D31
TBC1D31，即TBC1结构域家族成员31。别名Gm85、WDR67等。它在人类细胞中广泛表达，尤其在睾丸、淋巴结等组织中表达量较高。TBC1D31的作用机制涉及到其作为Rab GTPase活化蛋白，通过催化Rab22A的GTP水解，减少Rab22A介导的溶酶体内运输和EGFR降解，从而激活EGFR信号传导，并在肝细胞癌中发挥作用。TBC1D31可作为一个新的治疗靶点，用于治疗TBC1D31基因扩增或过表达的肝细胞癌患者。
热销产品
TBC1D31 Antibody (CSB-PA822197LA01HU)
验证数据
Immunohistochemistry analysis of human testis tissue using CSB-PA822197LA01HU at dilution of 1:100
Immunocytochemistry analysis of human glioma using CSB-PA822197LA01HU at dilution of 1:100
TBC1D31 Antibodies
TBC1D31 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA822197LA01HU | TBC1D31 Antibody | Human | ELISA, IHC |
| CSB-PA822197LB01HU | TBC1D31 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA822197LD01HU | TBC1D31 Antibody, Biotin conjugated | Human | ELISA |
TBC1D31 Proteins
TBC1D31 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP822197HU CSB-EP822197HU CSB-BP822197HU CSB-MP822197HU CSB-EP822197HU-B |
Recombinant Human WD repeat-containing protein 67 (WDR67), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
