SYK
SYK,即脾酪氨酸激酶,别名KSYK、p72syk。SYK由人类SYK基因编码,该基因广泛表达于造血细胞中,并涉及将激活的免疫受体耦合到介导多种细胞反应的下游信号事件,包括增殖、分化和吞噬作用。SYK的作用机制涉及其作为非受体型Tyr蛋白激酶家族成员,在B细胞受体(BCR)反应中扮演中心角色,作为上游激活器激活PI3K、PLCgamma2和Rac/cdc42等途径。SYK在适应性免疫受体信号传导中发挥着至关重要的作用,并且近期研究显示SYK还介导其他多样化的生物学功能,包括细胞粘附、先天免疫识别、破骨细胞成熟、血小板活化和血管发育等。SYK在自身免疫性疾病和血液恶性肿瘤中也发挥着至关重要的作用。
热销产品
SYK Antibody (CSB-PA022998LA01HU)
验证数据

Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA022998LA01HU at dilution of 1:100

Immunofluorescence staining of HepG2 cells with CSB-PA022998LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
SYK Antibodies
SYK for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA055006 | Phospho-SYK (Tyr323) Antibody | Human | ELISA,WB,IHC,IF |
CSB-PA572454 | SYK (Ab-323) Antibody | Human | ELISA,WB,IHC,IF |
CSB-PA556441 | Phospho-SYK (Tyr352) Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA938706 | SYK Antibody | Human | ELISA,WB |
CSB-PA000697 | Phospho-SYK (Y348) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA000698 | Phospho-SYK (Y525) Antibody | Human, Mouse, Rat, Monkey | WB, IHC, ELISA |
CSB-PA004198 | SYK Antibody | Human | WB, IHC, ELISA |
CSB-PA004199 | SYK Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA050187 | Phospho-SYK (Y352) Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA050188 | Phospho-SYK (Y323) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA050189 | SYK Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA050190 | SYK Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
CSB-PA050191 | SYK Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA832352 | SYK Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA436831 | SYK Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA022998LA01HU | SYK Antibody | Human | ELISA, IHC, IF |
CSB-PA022998LD01HU | SYK Antibody, Biotin conjugated | Human | ELISA |
SYK Proteins
SYK Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP022998HU CSB-EP022998HU CSB-BP022998HU CSB-MP022998HU CSB-EP022998HU-B |
Recombinant Human Tyrosine-protein kinase SYK (SYK) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SYK Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP022998MO CSB-EP022998MO CSB-BP022998MO CSB-MP022998MO CSB-EP022998MO-B |
Recombinant Mouse Tyrosine-protein kinase SYK (Syk) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SYK Proteins for Gallus gallus (Chicken)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP022998CH CSB-EP022998CH CSB-BP022998CH CSB-MP022998CH CSB-EP022998CH-B |
Recombinant Chicken Tyrosine-protein kinase SYK (SYK), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SYK Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP714515RA CSB-EP714515RA CSB-BP714515RA CSB-MP714515RA CSB-EP714515RA-B |
Recombinant Rat Tyrosine-protein kinase SYK (Syk) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |