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STMN2

STMN2,别名SCG10、SCGN10。它是一种由人类基因编码的微管相关蛋白,属于磷酸蛋白家族。STMN2在多种组织中表达,尤其在大脑和肾上腺中表达量较高。STMN2的作用机制涉及微管动力学和信号转导,它通过影响微管的稳定性来调控细胞周期、细胞迁移、信号传导和转运蛋白的功能。STMN2在神经元生长中起到调节作用,并被认为参与骨生成。STMN2的表达减少与唐氏综合症和阿尔茨海默病有关。STMN2的不同剪接转录变异体已被观察到,并且该基因的一个假基因位于染色体6的长臂上。STMN2在轴突发育和修复中起主要作用,促进正常轴突生长和再生所必需的微管不稳定性,其表达受到核反式反应DNA结合蛋白43 kDa (TDP-43)的强烈调控。

热销产品

Recombinant Human Stathmin-2 (STMN2) (CSB-EP853100HU)

验证数据

CSB-EP853100HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

STMN2 Antibody (CSB-PA853100LA01HU)

验证数据

CSB-PA853100LA01HU

Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA853100LA01HU at dilution of 1:100

CSB-PA853100LA01HU

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA853100LA01HU at dilution of 1:100

CSB-PA853100LA01HU

Immunofluorescent analysis of A549 cells using CSB-PA853100LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

STMN2 Antibodies

STMN2 for Homo sapiens (Human)

STMN2 Proteins

STMN2 Proteins for Homo sapiens (Human)