SLC16A11
SLC16A11，即溶质载体家族16成员11，别名MCT11。SLC16A11是一种单羧酸转运蛋白，负责丙酮酸的跨膜转运，参与脂质代谢过程，并位于内质网膜和质膜上。SLC16A11通过质子耦联机制转运单羧酸类物质，包括丙酮酸、乳酸、酮体和短链脂肪酸，其转运方向由细胞膜两侧的质子和单羧酸盐浓度梯度决定。SLC16A11的功能异常与多种疾病相关，如2型糖尿病、胰岛素抵抗和血脂代谢异常。SLC16A11在肝脏中表达，其变异可能通过影响肝脏细胞的乳酸转运和甘油三酯代谢功能，进而影响糖尿病的发生和发展。
热销产品
SLC16A11 Antibody (CSB-PA843323LA01HU)
验证数据
Western Blot
Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate
All lanes: SLC16A11 antibody at 3.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 48 kDa
Observed band size: 48 kDa
Immunofluorescence staining of A549 cells with CSB-PA843323LA01HU at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
SLC16A11 Antibodies
SLC16A11 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA808680 | SLC16A11 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA371613 | SLC16A11 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA843323LA01HU | SLC16A11 Antibody | Human | ELISA, WB, IF |
| CSB-PA843323LB01HU | SLC16A11 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA843323LC01HU | SLC16A11 Antibody, FITC conjugated | Human | |
| CSB-PA843323LD01HU | SLC16A11 Antibody, Biotin conjugated | Human | ELISA |
SLC16A11 Proteins
SLC16A11 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP843323HU CSB-EP843323HU CSB-BP843323HU CSB-MP843323HU CSB-EP843323HU-B |
Recombinant Human Monocarboxylate transporter 11 (SLC16A11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
