SLC10A2
SLC10A2,即溶质载体家族10成员2,别名ASBT、IBAT、ISBT。SLC10A2主要在回肠肠细胞顶端膜表达,负责将胆汁酸从肠腔内吸收到肠细胞中,是胆汁酸肠肝循环的关键转运蛋白。
SLC10A2参与胆汁酸和胆汁盐的转运,位于顶端质膜和细胞核中,是蛋白酶体复合物的一部分。SLC10A2对于维持胆汁酸的肠肝循环、胆固醇稳态以及肠道运动具有重要作用。功能异常可能导致与胆汁酸肠肝循环和胆固醇稳态失调相关的疾病,如腹泻、胆结石、炎症性肠病、便秘、Alagille综合征、家族性高甘油三酯血症、先天性慢性腹泻、肠易激综合征、非酒精性脂肪性肝炎(NASH)等。
热销产品
SLC10A2 Antibody (CSB-PA622519LA01HU)
验证数据

Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA622519LA01HU at dilution of 1:100

Immunofluorescent analysis of A431 cells using CSB-PA622519LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
SLC10A2 Antibodies
SLC10A2 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA622519LA01HU | SLC10A2 Antibody | Human | ELISA, IHC, IF |
CSB-PA622519LB01HU | SLC10A2 Antibody, HRP conjugated | Human | ELISA |
CSB-PA622519LC01HU | SLC10A2 Antibody, FITC conjugated | Human | |
CSB-PA622519LD01HU | SLC10A2 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA843819 | SLC10A2 Antibody | Human, Mouse | ELISA, WB |
SLC10A2 Proteins
SLC10A2 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP622519HU CSB-EP622519HU CSB-BP622519HU CSB-MP622519HU CSB-EP622519HU-B |
Recombinant Human Ileal sodium/bile acid cotransporter (SLC10A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-MP622519HU(A4) | Recombinant Human Ileal sodium/bile acid cotransporter (SLC10A2)-VLPs | Mammalian cell |