SELPLG
SELPLG，即选择素P配体，别名CLA、CD162、PSGL1、PSGL-1，是一种由人类SELPLG基因编码的糖蛋白，主要在骨髓细胞和受刺激的T淋巴细胞上表达。
SELPLG通过作为P-、E-和L-选择素的高亲和力反受体，介导白细胞与活化的血小板或表达选择素的内皮细胞的粘附，这一过程对于炎症期间白细胞的运输至关重要。SELPLG需要经过酪氨酸硫酸化和O-连接的聚糖添加唾液酸Lewis x四糖(sLex)的翻译后修饰，以实现其高亲和力结合活性。SELPLG在先天性和适应性免疫反应中发挥关键作用，其异常表达和基因多态性与免疫反应的缺陷有关。
热销产品
SELPLG Recombinant Monoclonal Antibody (CSB-RA567010A0HU)
验证数据
IHC image of CSB-RA567010A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
SELPLG Antibodies
SELPLG for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA006151 | SELPLG Antibody | Human | WB, ELISA |
| CSB-PA148952 | SELPLG Antibody | Human | ELISA,IHC |
| CSB-PA129120 | SELPLG Antibody | Human | ELISA,IHC |
| CSB-RA567010A0HU | SELPLG Recombinant Monoclonal Antibody | Human | ELISA, IHC |
SELPLG Proteins
SELPLG Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP621767HU CSB-EP621767HU CSB-BP621767HU CSB-MP621767HU CSB-EP621767HU-B |
Recombinant Human P-selectin glycoprotein ligand 1 (SELPLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SELPLG Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP730777MO CSB-EP730777MO CSB-BP730777MO CSB-MP730777MO CSB-EP730777MO-B |
Recombinant Mouse P-selectin glycoprotein ligand 1 (Selplg), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
