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S100A11

S100A11,即S100钙结合蛋白A11,别名S100a11、S100C。它是一种低分子量(10-14 kDa)的钙离子结合蛋白,属于S100蛋白家族。S100A11在多种组织中表达,可位于细胞质、细胞核,甚至细胞外围,通常以非共价键形成的同源二聚体存在。S100A11的作用机制涉及其与Ca2+的结合,这种结合触发构象变化,暴露出疏水口袋,从而促进与靶蛋白的相互作用。S100A11通过与多种靶蛋白结合,在多种生物学过程中发挥作用,包括调节细胞生长、凋亡、炎症反应和细胞骨架构建等。S100A11参与多种细胞活性及功能调控。它在调节细胞生长和凋亡、参与炎症反应、细胞膜修复及DNA修复等生物学功能中发挥作用。S100A11还参与癌症的发生发展,其在多种肿瘤中高表达,并且与某些癌症患者的不良预后有关。

热销产品

S100A11 Antibody (CSB-PA625010)

验证数据

CSB-PA625010

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA625010(S100A11 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA625010

Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hepg2 cells, A549 cells, Primary antibody: CSB-PA625010(S100A11 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 seconds

S100A11 Antibodies

S100A11 for Homo sapiens (Human)

S100A11 Proteins

S100A11 Proteins for Homo sapiens (Human)

S100A11 ELISA Kit

S100A11 ELISA Kit for Homo sapiens (Human)